narrow spectrum abx, short course = proven efficacy
--nitrofurantoin -> 100mg PO BIDx5d
or
--trimethoprim/sulfamethoxazole (TMP-SMX, Septra) -> 160/800mg = 1ds tab BIDx3d
- caveat: only if local resistance rates for e.coli are <20%
Alternatives
--ciprofloxacin -> 500mg PO BIDx3d (used to rx many things so don't want resistance)
or
--amoxicillin-clavulanic acid -> β lactams have decreased efficacy in UTI