Hypocomplementemic (low C3)
– Primary renal disease
- post infectious glomerulonephritis (post strep GN most common)
- membranoproliferative glomerulonephritis
- C3 nephropathy
– Systemic disease
- SLE (main)
- shunt nephritis
- sub acute bacterial endocarditis
Normocomplementemic (normal C3)
– Primary renal disease
- IgA nephropathy
- ANCA + pauci immune GN
– Systemic disease
- ANCA + ds (GPA granulomatosis w/ polyangiitis, MPA microscopic polyangiitis)
- Anti GBM ds (goodpasture ds)
- Henoch Schonlein Purpura
NB: so check for C3 in labs