What neurohumoral activation happens when the heart begins to fail?
Answer
when CO & systemic BP decreases
1) sympa is first activated (NE/E)
2) over days-weeks, RAAS is activated
3) last stage is non-osmotic release of vasopressin (seen in sickest pt's, measured by low serum Na)
-all 3 lead to augmented HR, contractility vasoconstriction, decreased renal excretion of Na/H2O -> restoration of circulating volume/preload & CO (initially adaptive)
Tags
#cardiology
Question
What neurohumoral activation happens when the heart begins to fail?
Answer
?
Tags
#cardiology
Question
What neurohumoral activation happens when the heart begins to fail?
Answer
when CO & systemic BP decreases
1) sympa is first activated (NE/E)
2) over days-weeks, RAAS is activated
3) last stage is non-osmotic release of vasopressin (seen in sickest pt's, measured by low serum Na)
-all 3 lead to augmented HR, contractility vasoconstriction, decreased renal excretion of Na/H2O -> restoration of circulating volume/preload & CO (initially adaptive)
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