Chronic severe aortic regurgitation will eventually result in left ventricular fibrosis and systolic dysfunction
As the ventricle dilates further, wall tension and filling pressure rise
Ejection fraction falls, reducing stroke volume and forward output
Irreversible structural changes may occur prior to the development of symptoms
-one of the insidious features of regurgitation is that by the time sx's occur, you're already in big trouble
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sarahcho - (no access) - 05 HANSEN MMMD 2015-16 Valvular Heart Disease - Aortic Stenosis.pdf, p35
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