Pathophysiology Obstruction to mitral inflow accentuates the pressure gradient from left atrium to left ventricle during diastole, resulting in elevated left atrial pressure Left atrial pressure overload causes: Pulmonary hypertension and interstitial / alveolar pulmonary edema due to back-transmission of pressure Left atrial dilation, resulting in 1. blood stasis and propensity for thromboembolism, and 2. risk of atrial fibrillation
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sarahcho - (no access) - 05 HANSEN MMMD 2015-16 Valvular Heart Disease - Mitral Stenosis.pdf, p11
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