Pathophysiology of chronic mitral regurg
-A state of left ventricular and left atrial volume overload
-Left ventricular systolic function may remain normal for years until fibrosis and progressive dilation herald a decline in ejection fraction
-The low-pressure left atrial “outlet” is a form of afterload reduction - and may mask clinical deterioration
---Left ventricular ejection fraction may be normal despite impaired contractile function
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sarahcho - (no access) - 05 HANSEN MMMD 2015-16 Valvular Heart Disease - Mitral Stenosis.pdf, p31
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