Constipation-predominant IBS tx
○ Abx (neomycin)
○ Antidepressants
○ Antispasmodics
○ Complementary & alt therapy (psychological tx, herbal therapies, peppermint oil)
○ 5-hydroxytryptamine 4 agonists (serious adverse events)
○ OTC laxatives
○ Probiotics
○ Selective c-2 chloride channel activator
○ exercise