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If 3 or more consecutive early losses or any mid-trimester loss, consider:
• Thrombophilia testing
• Hysterosonogram (HSG) to check for abnormalities of uterine cavity
• Genetic Counselling +/- maternal and paternal karyotyping
• Cervical cerclage at 13-14 weeks of pregnancy (for cervical insufficiency only)
• Medications: low dose ASA (if previous PET/or high risk for PET), evidence of previous placental abruption/thrombosis)
• Progesterone supplementation (some evidence in luteal phase defects and prevention of preterm labour.
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