Endocrine:
• ↑ size of thyroid gland
• ↑ basal metabolic rate
• ↑ total thyroid hormone (secondary to increased thyroid binding globulin)
• ↑ total and free cortisol
• ↓ total calcium secondary to decreased serum albumin
• ↑ PTH:
---• increased bone resorption
---• increased gut absorption
---• unchanged free calcium
• Increased bone turnover with no loss of density due to estrogen’s inhibition of resorption
• Diabetogenic tendencies: increased serum cortisol and increased insulin resistance
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