Therefore, at modest con- centrations, cholesterol decreases fl uidity. However, when it is present in high concentrations, cholesterol can substan- tially disrupt the ability of the phospholipids to interact among themselves, which increases fl uidity and lowers the gel-sol transition temperature.
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Sirre - (no access) - Boron and Boulpaep Medical Physiology 2e Update.pdf, p25
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