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#biochem
Th e backbones (specifi cally the phosphates) need to be separated as far as possible and be exposed to solvent to minimize electrostatic repulsions.
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Th e backbones (specifi cally the phosphates) need to be separated as far as possible and be exposed to solvent to minimize electrostatic repulsions. Th e bases, in turn, need to stack to optimize the van der Waals and electrostatic interactions between them, as well as to form mutually stabilizing hydrogen bonds where possible.<

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