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#biochem
the major groove in the A-form is deeper and narrower than it is in B-form DNA, while the minor groove is wider and shallower
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the major groove in the A-form is deeper and narrower than it is in B-form DNA, while the minor groove is wider and shallower (Figure 2.18 and Figure 2.19). Th e narrowing and deepening of the major groove in A-form helices means that it is more diffi cult for proteins to read out the sequence-specifi c in

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