Why is it more difficult for proteins to interact with A-form DNA compared to B-form?
Answer
Th e narrowing and deepening of the major groove in A-form helices means that it is more diffi cult for proteins to read out the sequence-specifi c information at the edges of the bases in A-form helices (that is, α helices cannot readily enter the narrower major groove of the A-form helix).
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#biochem
Question
Why is it more difficult for proteins to interact with A-form DNA compared to B-form?
Answer
?
Tags
#biochem
Question
Why is it more difficult for proteins to interact with A-form DNA compared to B-form?
Answer
Th e narrowing and deepening of the major groove in A-form helices means that it is more diffi cult for proteins to read out the sequence-specifi c information at the edges of the bases in A-form helices (that is, α helices cannot readily enter the narrower major groove of the A-form helix).
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Open it Th e narrowing and deepening of the major groove in A-form helices means that it is more diffi cult for proteins to read out the sequence-specifi c information at the edges of the bases in A-form helices (that is, α helices cannot readily enter the narrower major groove of the A-form helix).
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