ADDD EFFIL MOOPPPS

Acetaminophen:
- Blocks pain impulse
generation, inhibits
hypothalamic heatregulating
center to
produce antipyresis
-Pain, Fever
-May cause
hepatotoxicity at high
doses. Caution use in
patients with hepatic
impairment

Dimenhydrinate
(Gravol®)
-Blocks chemoreceptor
trigger zone, diminishes
vestibular stimulation
-Nausea,
Vomiting
-May cause sedation

Diphenhydramine
(Benadryl®)
-Competes with
histamine for H1
receptor sites on
effector cells in GIT,
respiratory tract, blood
vessels
-Pruritis
-May cause sedation

Dexamethasone:
- Anti‐inflammatory;
better taste, lower
volume than prednisone
-Asthma
Croup
-Immunosuppression
Weight gain
Hyperglycaemia
Hypertension

Epinephrine
Inhaled:
-Stimulates α, β1 and β2
adrenergic receptors to
relax smooth muscles of
bronchial tree
-Bronchiolitis,
Croup
-Can cause tachycardia

Iron (ferrous
fumerate,
ferrous
sulphate)
-Replaces iron
-Iron deficiency
-Can cause constipation,
black stools

Fluticasone
-Inhaled steroid, minimal
systemic absorption
-Asthma
(inhaled)
Allergic
Rhinitis
(intranasal)
-Ask patients to have a
drink or gargle after
inhaled use to clear
from back of throat.

Ibuprofen
-Reversibly inhibits COX
1 and 2 to decrease
prostaglandin
formation.
-Pain, Fever
-Can cause GI irritation.
Caution use in renal
impairment

Lorazepam
-Benzodiazepine. Binds
to GABA Rc complex and
enhances affinity of
GABA for its Rc site on
the same complex.
-Seizure
Anxiety
disorder
Severe nausea
-Anterograde amnesia,
risk of paradoxical
effects. Risk of CNS
depression and
excessive sedation.

Morphine
-Binds to opiate
receptors in the CNS to
inhibit pain pathways.
-Pain
-May cause CNS
depression

Omeprazole
-Inhibits parietal cell
H+/K+ ATP pump to
suppress basal and
stimulated acid
secretion
-GERD
-Fairly well tolerated.
Can cause headache, GI
side effects (abdominal
pain, diarrhea, nausea)

Ondansetron
-Selective 5‐HT3‐
receptor antagonist,
blocking serotonin, both
peripherally on vagal
nerve terminals and
centrally in the
chemoreceptor trigger
zone
-Post‐operative
nausea &
vomiting,
gastroenteritis,
cyclic vomiting
-Can cause QTc
prolongation. Caution
use in patients with
known QT
prolongation or in
patients on other QTc
prolonging agents.

Phenobarbital
-Long acting barbiturate
with sedative, hypnotic
and anticonvulsant
properties
-Seizures
-Can cause CNS
depression

Polyethylene
Glycol 3350
-Osmotic agent. Causes
water retention in stool
to increase stool
frequency
-Constipation
-Can cause abdominal
bloating, cramping,
nausea and diarrhea

Prednisone
-Decreases neutrophil
migration and reverses
capillary permeability
to prevent or control
inflammation
-Asthma
-Immunosuppression,
weight gain,
hyperglycemia,
hypertension

Salbutamol
-Acts on β2 receptors to
relax bronchial smooth
muscles
-Asthma
-Tachycardia,
hypokalemia,
restlessness