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Kernicterus is the pathological term used to describe staining of the basal ganglia and cranial nerve nuclei by bilirubin. Kernicterus also describes the clinical condition that results from the toxic effects of high levels of unconjugated bilirubin.
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CLIPP 8 - neonatal jaundiceociated with hyperbilirubinemia and may result from both unconjugated and conjugated forms of bilirubin.
Unconjugated hyperbilirubinemia can have serious consequences.
Kernicterus
Definition
<span>Kernicterus is the pathological term used to describe staining of the basal ganglia and cranial nerve nuclei by bilirubin. Kernicterus also describes the clinical condition that results from the toxic effects of high levels of unconjugated bilirubin.
Sequelae
Severely affected newborn infants may:
lose the suck reflex become lethargic develop hyperirritability and seizures, and ultimately die & Summary
| status | not read | | reprioritisations | |
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| last reprioritisation on | | | suggested re-reading day | |
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Details