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Antibody-positive hemolysis is labeled "direct Coombs" or "direct antibody test (DAT)" positive. The most common forms of antibody-positive hemolysis include:
Hemolysis
Rh incompatibility (mother is Rh-negative and baby is Rh-positive) ABO incompatibility (mother is type O and baby is type A or B) Incompatibilities with minor blood group antigens (much less common)
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CLIPP 8 - neonatal jaundiceof physiologic jaundice.
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In pathological processes hemolysis causes breakdown of red blood cells (RBCs). The hemoglobin released is metabolized to unconjugated bilirubin, which results in jaundice.
<span>Antibody-positive hemolysis is labeled "direct Coombs" or "direct antibody test (DAT)" positive. The most common forms of antibody-positive hemolysis include:
Hemolysis
Rh incompatibility (mother is Rh-negative and baby is Rh-positive) ABO incompatibility (mother is type O and baby is type A or B) Incompatibilities with minor blood group antigens (much less common)
Antibody-negative hemolysis occurs in infants who have red blood cell membrane defects (e.g., spherocytosis) or red blood cell enzyme defects (glucose-6- phosphate dehydrog Summary
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