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Antibody-positive hemolysis is labeled "direct Coombs" or "direct antibody test (DAT)" positive. The most common forms of antibody-positive hemolysis include:

Hemolysis

Rh incompatibility (mother is Rh-negative and baby is Rh-positive) ABO incompatibility (mother is type O and baby is type A or B) Incompatibilities with minor blood group antigens (much less common)

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CLIPP 8 - neonatal jaundice
of physiologic jaundice. 4/22 In pathological processes hemolysis causes breakdown of red blood cells (RBCs). The hemoglobin released is metabolized to unconjugated bilirubin, which results in jaundice. <span>Antibody-positive hemolysis is labeled "direct Coombs" or "direct antibody test (DAT)" positive. The most common forms of antibody-positive hemolysis include: Hemolysis Rh incompatibility (mother is Rh-negative and baby is Rh-positive) ABO incompatibility (mother is type O and baby is type A or B) Incompatibilities with minor blood group antigens (much less common) Antibody-negative hemolysis occurs in infants who have red blood cell membrane defects (e.g., spherocytosis) or red blood cell enzyme defects (glucose-6- phosphate dehydrog


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