#ir #peds
Metabolic errors
Crigler-Najjar syndrome: hyperbilirubinemia results from decreased bilirubin clearance caused by deficient or completely absent UDPGT. Galactosemia and hypothyroidism also have jaundice as prominent clinical findings.
These congenital disorders are detected by neonatal screening.
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CLIPP 8 - neonatal jaundicedice and occurs in a variety of conditions, including:
Extensive bruising from birth trauma Large cephalohematoma or other hemorrhage (e.g., intracranial) Polycythemia Swallowed blood (large amounts) during delivery.
<span>Metabolic errors
Crigler-Najjar syndrome: hyperbilirubinemia results from decreased bilirubin clearance caused by deficient or completely absent UDPGT. Galactosemia and hypothyroidism also have jaundice as prominent clinical findings.
These congenital disorders are detected by neonatal screening.
Ethnicity
Hyperbilirubinemia is more common in Asian newborn infants than in Caucasian infants and is less common in black infants.
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