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Crigler-Najjar syndrome

Due to the absence or low levels of UDP glucuronosyltransferase 1 family, polypeptide A1. Can cause severe (type I) or mild/moderate (type II) jaundice. Also very rare.

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CLIPP 8 - neonatal jaundice
yltransferase) is a relatively common cause of harmless jaundice (~5% of the population). Final diagnosis usually does not occur until later in life, when it is found that hyperbilirubinemia persists, with no other abnormalities. <span>Crigler-Najjar syndrome Due to the absence or low levels of UDP glucuronosyltransferase 1 family, polypeptide A1. Can cause severe (type I) or mild/moderate (type II) jaundice. Also very rare. Studies Evaluation of Neonatal Hyperbilirubinemia Test Indication Maternal ABO and Rh typing and screen for unusual isoimmune antibod


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