What are the non immune causes of Haemolytic anaemia ?
Answer
Direct antiglobulin/Coombs – ve AIHA : ( 2 % of all AIHA ) Autoimmune hepatitis; hepatitis B & C ; post flu and other vaccinations; drugs (piperacillin, rituximab).
Microangiopathic haemolytic anaemia (MAHA): A mechanical disruption of RBCs in circulation, causing intravascular haemolysis and schistocytes. Causes include haemolytic – uraemic syndrome, TTP, DIC, pre-eclampsia, eclampsia.
Infection: Malaria: RBC lysis and ‘blackwater fever’ (haemoglobinuria).
What are the non immune causes of Haemolytic anaemia ?
Answer
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Tags
#haematology #medicine
Question
What are the non immune causes of Haemolytic anaemia ?
Answer
Direct antiglobulin/Coombs – ve AIHA : ( 2 % of all AIHA ) Autoimmune hepatitis; hepatitis B & C ; post flu and other vaccinations; drugs (piperacillin, rituximab).
Microangiopathic haemolytic anaemia (MAHA): A mechanical disruption of RBCs in circulation, causing intravascular haemolysis and schistocytes. Causes include haemolytic – uraemic syndrome, TTP, DIC, pre-eclampsia, eclampsia.
Infection: Malaria: RBC lysis and ‘blackwater fever’ (haemoglobinuria).