Cephalosporins, such as cefazolin, can cause AKI from acute interstitial nephritis. Urine findings include leukocytes, erythrocytes, and leukocyte casts. Fever, maculopapular rash, peripheral eosinophilia, and eosinophiluria can also occur. Onset of AKI after drug exposure ranges from 3 to 5 days with a second exposure, to as long as several weeks to months with a first exposure.
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- (no access) - MKSAP_17.pdf, p3416
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