Oral demeclocycline results in renal resistance to antidiuretic hormone and can be effective in treating patients with SIADH. However, it has been associated with acute kidney injury and is generally reserved for patients who have failed other therapies. It should be used with caution in patients with preexisting kidney or liver disease.
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ELBOMBARDO - (no access) - MKSAP_17.pdf, p3514
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