Rasburicase rapidly converts uric acid to allantoin, which is 5 to 10 times more soluble than uric acid and readily excreted through the kidney. Rasburicase has a much faster action than allopurinol and can decrease serum urate levels within 4 hours of administration.
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ELBOMBARDO - (no access) - MKSAP_17.pdf, p3564
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