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Secondary FSGS is believed to result from an adaptive response to glomerular hypertrophy or hyperfiltration associated with a number of conditions (including obesity) in which the glomerular filtration rate may be markedly increased; glomeruli on biopsy are often enlarged, reflecting hyperfiltration with only mild foot process effacement. These patients have minimal edema and rarely have the full spectrum of the nephrotic syndrome.
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owner: ELBOMBARDO - (no access) - MKSAP_17.pdf, p3571


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