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simvastatin) that undergoes significant metabolism via the cytochrome P450 3A4 (CYP3A4) pathway; lovastatin and, to a lesser extent, amlodipine are also metabolized through this pathway. Several calcium channel blockers inhibit or are metabolized through the CYP3A4 pathway and can increase the risk of statin myopathy
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owner: ELBOMBARDO - (no access) - MKSAP_17.pdf, p3575


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