The prokinetic agent metoclopramide has demonstrated limited efficacy. The benefits of its use should be weighed against the substantial risk of potential neurologic side effects, which include akathisia (nervousness, restlessness, anxiety, agitation), parkinsonism (bradykinesia, resting tremor, and rigidity), and tardive dyskinesia (involuntary, repetitive, tic- like movements that involve primarily the facial muscles but also the extremities, digits, hips, or torso).