endoscopic assessment for Barrett esophagus (BE) in patients with chronic reflux symptoms may be appropriate in specific patients. It is reasonable to consider screening men older than 50 years with gastroesophageal reflux disease (GERD) symptoms for more than 5 years and additional risk factors (nocturnal reflux symptoms, hiatal hernia, elevated BMI, tobacco use, and intra-abdominal distribution of fat) to detect esophageal adenocarcinoma and BE.