Diffuse esophageal spasm is usually characterized by dysphagia or chest pain but not food impaction. Manometry shows intermittent, high- amplitude, simultaneous, nonperistaltic contractions in response to swallowing. Findings of a “corkscrew esophagus” (caused by multiple simultaneous contractions) on barium swallow are typical of diffuse esophageal spasm.
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ELBOMBARDO - (no access) - MKSAP_17.pdf, p2730
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