The most appropriate management is serial monitoring of liver enzymes. This patient has acute hepatitis B without evidence of marked liver dysfunction (such as markedly increased INR or hepatic encephalopathy). Typical clinical symptoms include malaise, fatigue, nausea, and right upper quadrant discomfort. Jaundice and cholestasis can develop 1 to 2 weeks after the onset of symptoms. Acute hepatitis B infection will resolve (defined as clearance of hepatitis B surface antigen within 6 months) in 90% of adult patients. Serial monitoring of liver enzymes and markers of liver synthetic function is the most appropriate management strategy