Transdermal drug administration can provide pro longed continuous administrati on for some drugs. However, the stratum corneum is an effec- tive barrier to all but small, lipid-so lub le drugs (eg, clonidine, nitroglycerin, scopolamine, fentanyl, and free-base local anesthetics
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- (no access) - Butterworth, Morgan and Mikhail's Clinical Anesthesiology 5, p144
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