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Sevoflurane is administered clinically in an amount that is 1.3- to 1.4-fold the MAC (mini- mum alveolar concentration), or the dose at which 50% of the patients do not move on surgical stimulation. The MAC can be lethal if the volume percentage delivered is increased to 1.7- to 2.0-fold and maintained for a prolonged period of time.
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owner: Hadassah1 - (no access) - Nagelhout Nurse Anesthesia 5th Ed.pdf, p74


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