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Severe sepsis meets the aforementioned criteria and is associated with organ dysfunction, hypoperfusion, or hypotension
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e presence of bacteria within the bloodstream, but this condition does not always lead to SIRS or sepsis . Sepsis is the systemic response to infection and is defined as the presence of SIRS in addition to a documented or presumed infection. <span>Severe sepsis meets the aforementioned criteria and is associated with organ dysfunction, hypoperfusion, or hypotension. (See Etiology, Treatment, and Medication.) Sepsis-induced hypotension is defined as "the presence of a systolic blood pressure of less than 90 mm Hg or a reduction of

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