Matrix of the mitochondrion: This gel-like solution in the interior of mitochondria is 50% protein. These molecules include the enzymes responsible for the oxidation of pyruvate, amino acids, fatty acids (by β-oxidation), and those of the tricarboxylic acid (TCA) cycle. The synthesis of glucose, urea, and heme occur partially in the matrix of mitochondria. In addition, the matrix contains NAD + and FAD (the oxidized forms of the two coenzymes that are required as hydrogen acceptors) and ADP and P i , which are used to produce ATP. [Note: The matrix also contains mitochondrial RNA and DNA (mtRNA and mtDNA) and mitochondrial ribosomes.]
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- (no access) - Lippincott's Biochemistry.pdf, p82
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