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Question
PTH-mediated effects in bone involve..
Answer
osteoblast activation and stimulation of genes vital to the processes of degradation of the extracellular matrix and bone remodeling (collagenase-3),
production of growth factors (insulin-like growth factor 1),
stimulation and recruitment of osteoclasts (RANKL and interleukin 6).
PTH also increases the number of osteoblasts, by decreasing their apoptosis and increasing their proliferation
Question
PTH-mediated effects in bone involve..
Answer
?
Question
PTH-mediated effects in bone involve..
Answer
osteoblast activation and stimulation of genes vital to the processes of degradation of the extracellular matrix and bone remodeling (collagenase-3),
production of growth factors (insulin-like growth factor 1),
stimulation and recruitment of osteoclasts (RANKL and interleukin 6).
PTH also increases the number of osteoblasts, by decreasing their apoptosis and increasing their proliferation
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pdf
owner:
Scutboy
- (no access) - Endocrine Physiology 4th Edition.pdf, p116
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