The US military can destroy or neutralize the S-300, but it would need to devote significant assets and time to do so. US air operations in the Middle East over Syria and Iraq are not currently constrained by any requirement to use stealth aircraft. Because stealth aircraft have higher operational and maintenance costs and generally carry less ordnance than nonstealth aircraft, the US does not typically assign stealth aircraft to routine operations in uncontested airspace, such as the current campaign against ISIS. In the absence of the S-300 system, nonstealth aircraft currently assigned to conduct air strikes against ISIS could, on a very short timeline, be retasked to conduct operations against Iran.