A survey in the United States reported an overall CMV seroprevalence rate of 50.4%. The prevalence increases with age; in children ages 1 to 5, it may be as low as 20.7%, but it approaches 100% in older adults in de- veloping countries ( 3, 4). CMV seroprevalence rate varies widely with (a) geographic location, with higher rates in developing countries; (b) age, with the rate in- creasing directly with older age; and (c) socioeconomic status, with highest seroprevalence in crowded and economically challenged populations.
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