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Paget’s disease: pale cells with adenocarcinoma staining features.

Carcinoembryonic antigen (CEA), EMA, CK-7, CK-8, usually positive.

Mucin in cytoplasm is often positive with mucicarmine, Alcian blue, colloidal iron, and PAS with and without diastase.

Basal cells are often compressed and uninvolved. No dyskeratosis

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Paget’s disease: pale cells with adenocarcinoma staining features. Carcinoembryonic antigen (CEA), EMA, CK-7, CK-8, usually positive. Mucin in cytoplasm is often positive with mucicarmine, Alcian blue, colloidal iron, and PAS with and without diastase. Basal cells are often compressed and uninvolved. No dyskeratosis Bowen’s disease (squamous cell carcinoma in situ, 18.10): pale keratinocytes may be present which contain glycogen (PAS positive, diastase labile) with frequent dyskeratosis (1.27). Ful

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owner: gss4 - (no access) - book_Practical-Dermatopathology.pdf, p23


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