When the sample size is very small, we should only ask relatively simple questions, while more complex questions can be addressed with larger sample sizes.
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Open it Fourth, we have to match our ambitions in research questions with the effective sample size that is available. When the sample size is very small, we should only ask relatively simple questions, while more complex questions can be addressed with larger sample sizes. A question such as: “What are the most important predic- tors in this prediction problem” is actually more complex than a question such as “What are the predictions of the outcome givenOriginal toplevel document (pdf)
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gss4 - (no access) - BOOK_steyerberg_Clinical prediction models.pdf, p31
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