The parasite Plasmodium vivax, responsible for 7.5 million malaria cases worldwide, remains understudied. Not much is known about its dormant stage in the liver. An international team has developed a system to breed these parasites in the lab and then infect cultured human liver cells with it. This can help establish a robust liver stage assay in P. vivax-endemic regions such as India.
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Unknown titleRINT A A A Important step: The improved methodwas developed for breeding A. stephensi mosquitoes in the lab. | Photo Credit: nopparit The method infects liver cells with mosquito-bred parasites <span>The parasite Plasmodium vivax, responsible for 7.5 million malaria cases worldwide, remains understudied. Not much is known about its dormant stage in the liver. An international team has developed a system to breed these parasites in the lab and then infect cultured human liver cells with it. This can help establish a robust liver stage assay in P. vivax-endemic regions such as India. Mosquitoes inject the sporozoite (spore-like) stage of the parasite into the skin when they bite, and the sporozoites travel to the liver. “Imagine some 50 parasites enter our liver, ea Summary
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