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A small trial (Nix-TB) undertaken at three sites in South Africa to test the safety and efficacy of three oral drugs — bedaquiline, pretomanid and linezolid — in 109 patients (57 males and 56 females were HIV positive) with extensively drug-resistant TB (XDR-TB) and multidrug-resistant TB (MDR-TB) showed encouraging results — treatment success rate was 90%. The favourable results held true regardless of the HIV status of the patients.
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nts is at par with the success rate seen while treating drug-sensitive TB. | Photo Credit: pittawut The small trial using three oral drugs in 109 patients showed a treatment success rate of 90% <span>A small trial (Nix-TB) undertaken at three sites in South Africa to test the safety and efficacy of three oral drugs — bedaquiline, pretomanid and linezolid — in 109 patients (57 males and 56 females were HIV positive) with extensively drug-resistant TB (XDR-TB) and multidrug-resistant TB (MDR-TB) showed encouraging results — treatment success rate was 90%. The favourable results held true regardless of the HIV status of the patients. The treatment using the three oral drugs lasted for 26 weeks and was followed-up for six months after the end of the treatment. Patients received the treatment daily for 26 weeks. The t


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