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Their choice of landmark time points was baseline, 3 years, 4 years, 5 years, and 7 years, a data-driven choice based on exponential curves that best fit the observed survival curve.
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A comparison of landmark methods and time-dependent ROC methods to evaluate the time-varying performance of prognostic markers for survival outcomes | Diagnostic and Prognostic Research | Full Text
didate markers measured in the study. They carried out landmark analyses to summarize different segments of follow-up with the eventual goal of determining which markers dominated each segment. <span>Their choice of landmark time points was baseline, 3 years, 4 years, 5 years, and 7 years, a data-driven choice based on exponential curves that best fit the observed survival curve. They measured the time-varying associations of the different variables by fitting univariate Cox models for each marker at each landmark time point. The resulting hazard ratios and asso


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