MicroRNAs (miRNAs) are members of
non-coding RNAs that range in size from 17 to 25 nucleotides. miRNAs regulate a large variety of biological functions in plants and animals.
[72] So far, in 2013, about 2000 miRNAs have been discovered in humans and these can be found online in a miRNA database.
[73] Each miRNA expressed in a cell may target about 100 to 200 messenger RNAs(mRNAs) that it downregulates.
[74] Most of the downregulation of mRNAs occurs by causing the decay of the targeted mRNA, while some downregulation occurs at the level of translation into protein.
[75]
If you want to change selection, open document below and click on "Move attachment"
Epigenetics - Wikipediay of sperm RNA is transmitted from the father, but there is recent evidence that this epigenetic information can lead to visible changes in several generations of offspring.[71] MicroRNAs[edit] <span>MicroRNAs (miRNAs) are members of non-coding RNAs that range in size from 17 to 25 nucleotides. miRNAs regulate a large variety of biological functions in plants and animals.[72] So far, in 2013, about 2000 miRNAs have been discovered in humans and these can be found online in a miRNA database.[73] Each miRNA expressed in a cell may target about 100 to 200 messenger RNAs(mRNAs) that it downregulates.[74] Most of the downregulation of mRNAs occurs by causing the decay of the targeted mRNA, while some downregulation occurs at the level of translation into protein.[75] It appears that about 60% of human protein coding genes are regulated by miRNAs.[76] Many miRNAs are epigenetically regulated. About 50% of miRNA genes are associated with CpG islands,[ Summary
| status | not read | | reprioritisations | |
|---|
| last reprioritisation on | | | suggested re-reading day | |
|---|
| started reading on | | | finished reading on | |
|---|
Details