Eq. (2.13) predicts that the substrate concentration is determined by the dilution rate. In effect, this occurs by growth of the cells depleting the substrate to a concen- tration that supports the growth rate equal to the dilution rate. If substrate is depleted below the level that supports the growth rate dictated by the dilution rate, the follow- ing sequence of events takes place: 1. The growth rate of the cells will be less than the dilution rate and they will be washed out of the vessel at a rate greater than they are being produced, resulting in a decrease in biomass concentration. 2. The substrate concentration in the vessel will rise because fewer cells are left in the vessel to consume it. 3. The increased substrate concentration in the vessel will result in the cells growing at a rate greater than the dilution rate and biomass concentration will increase. 4. The steady state will be reestablished.
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[default - edit me]
Answer
Eq. (2.13) predicts that the substrate concentration is determined by the dilution rate. In effect, this occurs by growth of the cells depleting the substrate to a concen- tration that supports the growth rate equal to the dilution rate. If substrate is depleted below the level that supports the growth rate dictated by the dilution rate, the follow- ing sequence of events takes place: 1. The growth rate of the cells will be less than the dilution rate and they will be washed out of the vessel at a rate greater than they are being produced, resulting in a decrease in biomass concentration. 2. The substrate concentration in the vessel will rise because fewer cells are left in the vessel to consume it. 3. The increased substrate concentration in the vessel will result in the cells growing at a rate greater than the dilution rate and biomass concentration will increase. 4. The steady state will be reestablished.
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owner: stuckonrepeat21 - (no access) - Principles of Fermentation Technology (Peter F Stanbury, Allan Whitaker etc.) (z-lib.org).pdf, p41
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