TSGs can be grouped into the following categories: caretaker genes, gatekeeper genes, and more recently landscaper genes.
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Tumor suppressor gene - Wikipediathis could allow the cell to grow abnormally. The loss of function for these genes may be even more significant in the development of human cancers, compared to the activation of oncogenes.[2] <span>TSGs can be grouped into the following categories: caretaker genes, gatekeeper genes, and more recently landscaper genes. Caretaker genes ensure stability of the genome via DNA repair and subsequently when mutated allow mutations to accumulate.[3] Meanwhile, gatekeeper genes directly regulate cell growth b Summary
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