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Caretaker genes ensure stability of the genome via DNA repair and subsequently when mutated allow mutations to accumulate. [3]
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Tumor suppressor gene - Wikipedia
velopment of human cancers, compared to the activation of oncogenes.[2] TSGs can be grouped into the following categories: caretaker genes, gatekeeper genes, and more recently landscaper genes. <span>Caretaker genes ensure stability of the genome via DNA repair and subsequently when mutated allow mutations to accumulate.[3] Meanwhile, gatekeeper genes directly regulate cell growth by either inhibiting cell cycle progression or inducing apoptosis.[3] Lastly landscaper genes regulate growth by contributing t


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