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on 01-Aug-2015 (Sat)

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Flashcard 150901269

Tags
#haematology #medicine
Question
What are the side effects with Erythropoietin use ?
Answer
  • Fu-like symptoms
  • Hypertension
  • Mild rise in the platelet count
  • Thromboembolism

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Flashcard 150901276

Tags
#haematology #medicine
Question
What condition should be consider if microcytic anaemia is not responding to iron?
Answer
Sideroblastic Anaemia

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Flashcard 150901283

Tags
#haematology #medicine
Question
What condition is Koilonychia found in?
Answer
Iron Deficiency Anaemia

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Flashcard 150901290

Tags
#haematology #medicine
Question
What is Anisocytosis ?
Answer
Variation in RBC size
  • Megaloblastic Anaemia
  • ​thalassaemia
  • IDA

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Flashcard 150901300

Tags
#haematology #medicine
Question
What are condition that cause Acanthocytes ?
Answer
  • Splenectomy
  • Alcoholic liver disease
  • Abetalipoproteinaemia
  • Spherocytosis

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Flashcard 150901307

Tags
#haematology #medicine
Question
What is Acanthocytes ?
Answer
Spicules on RBCs (unstable RBC membrane lipid structure)

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Flashcard 150901314

Tags
#haematology #medicine
Question
What are Howell – Jolly bodies ?
Answer
DNA nuclear remnants in RBCs, which are normally removed by the spleen.

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Flashcard 150901321

Tags
#haematology #medicine
Question
What conditions are Howell – Jolly bodies seen in ?
Answer
  • Post-splenectomy
  • Hyposplenism
    • Sickle-cell disease
    • Coeliac disease
    • Congenital
    • Ulcerative Colitis /Crohn's Disease
    • Myeloproliferative disease
    • Amyloid
  • Dyserythopoietic states:
    • Myelodysplasia
    • Megaloblastic anaemia

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Flashcard 150901328

Tags
#haematology #medicine
Question
What are Tear-Drop RBCs seen in ?
Answer
Extramedullary Haemopoiesis

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Flashcard 150901338

Tags
#haematology #medicine
Question
What conditions are Target cells seen on blood film in ?
Answer
  • Liver disease
  • Hyposplenism
  • Thalassaemia

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Flashcard 150901345

Tags
#haematology #medicine
Question
What conditions are Schistocytes seen on blood film in ?
Answer
  • Microangiopathic anaemia
  • Haemolytic uraemic syndrome
  • Thrombotic thrombocytopenic purpura
  • Pre-eclampsia

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Flashcard 150901352

Tags
#haematology #medicine
Question
What is a Rouleaux formation in Haematology ?
Answer
Red cells stacked on each other

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Flashcard 150901359

Tags
#haematology #medicine
Question
What is the effect of a Rouleaux formation on ESR ?
Answer
Increased ESR

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Flashcard 150901366

Tags
#haematology #medicine
Question
What two conditions cause Spherocytes on Blood Film ?
Answer
  • Hereditary spherocytosis
  • Autoimmune haemolytic anaemia

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Flashcard 150901373

Tags
#haematology #medicine
Question
What are Schistocytes ?
Answer
Fragmented RBCs sliced by fibrin bands, in intravascular haemolysis

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Flashcard 150901380

Tags
#haematology #medicine
Question
What are Spherocytes
Answer
Spherical cells

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Flashcard 150901387

Tags
#haematology #medicine
Question
What do Reticulocytes indicate ?
Answer
Active Erythropoiesis

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Flashcard 150901394

Tags
#haematology #medicine
Question
What indicates a hypersegmented polymorph (Hypermature White Cell) ?
Answer
> 5 lobes to nucleus

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Flashcard 150901401

Tags
#haematology #medicine
Question
What is a Right shift on Blood Film indicated by?
Answer
Hypermature white cells

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Flashcard 150901408

Tags
#haematology #medicine
Question
What are the causes of a Right shift on Blood Film?
Answer
  • Megaloblastic anaemia
  • Uraemia
  • Liver disease

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Flashcard 150901415

Tags
#haematology #medicine
Question
What is Poikilocytosis ?
Answer
Variation in RBC shape

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Flashcard 150901422

Tags
#haematology #medicine
Question
What are Pappenheimer bodies
Answer
Granules of siderocytes containing iron

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Flashcard 150901429

Tags
#haematology #medicine
Question
In what conditions are Pappenheimer bodies seen ?
Answer
  • Lead poisoning
  • Carcinomatosis
  • Post-splenectomy

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Flashcard 150901436

Tags
#haematology #medicine
Question
What is a Leukaemoid reaction ?
Answer
A marked leucocytosis

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