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#asset-swap #finance
hese things may also be influenced to some extent by the price the fi rm is willing to pay to increase its capacity quickly

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The upp er respiratory tract (especially the nose) functions as the principal heat and moisture exchanger (HME) to bring inspired gas to body temper- ature and 100% humidity in its passage to the alveoli.

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The primary function of the larynx is to protect the lungs from aspiration of foreign material. The larynx also functions in respiration and in phona- tio n.

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The 3 unpaired laryngeal C"artilages are the epiglottis, thyroid, and cricoid . The 3 paired laryngeal cartilages are the arytenoids, cuneiforms, and corniculates.

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The posterior cricoarytenoids abduct (o pen) the cords; the lateral cricoarytenoids adduct (close) the cords.

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If "dilates" means that the space between the cords wide ns (the cords ab- duct), the answer is the posterior cricoarytenoids.

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The cricothyroid muscle lengthens (lightens or tenses) the vocal cords. The voice will go up in pitch when the cords are tensed.

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The thyroarytenoid relaxes the cords

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The recurrent laryngeal nerve, which is a branch of the vagus, provides sensation below the cords.

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he internal branch of the superior lary ngeal nerve, which also is a branch of the vagus , provides sensations above the cords

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The internal branch of the superior laryngeal nerve supplies sensory fibers to the anterior and posterior surfaces of the epiglottis.

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Stimulation of the superior laryngeal nerves may cause laryngospasm.

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The cricothyroids are the muscles involved in laryngospasm. The crico- thyroids adduct and tense the true vocal cords.

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Laryngospasm is mediated by the external branch of the superior laryngeal nerve.

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The external branch of superior laryngeal nerve p rovi des motor innervation to the cricothyroid muscle.

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When the recurren t laryngeal nerve is damaged, the paralyzed vocal co rd ass um es a position intermediate between the abducted and adducted states.

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The paralyzed cord cannot adduct. The late ral cricoarytenoid causes adduct io n of the cords.

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The diaphragm is innervated by the phrenic nerve originating from C3, C4, CS.

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The phrenic nerve arises chiefly from the 4lh cervical nerve with contributions from the 3•d and s•h cervical nerves. Remember: C3, C4, CS keeps the diaphragm alive.

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Dead space ls that portion of the tidal vo lume that does not participate in gas exchange.

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A right -to-left shunt occurs when some portion of the right heart's outp ut is sh unt ed past the alveoli to the left ventri cle

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An intrapulmonary shunt is present when blood passes from the pulmo - nary artery lo th e pulmonary ve in through capillaries of unventilated or poo rl y ventila ted alveoli.

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A shunt causes a decrease in P. 02 .

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ypoxemia and tiss ue hypoxia result if a shunt develops and the patient is breathing room air and possibly also when breathing a high inspired oxygen concentrations

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An increase in P ,CO z is a consequence of mild dead spacing .

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Hypoxic pulmonary vasoconstriction (HPV} decreases shunt

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HPV reduces perfusion to unv entilated or poorly ventilated alveoli, and reduces the sever i ty of the shunt

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The PA0 2-P.02 gradient is normaJly about 5-15 mmHg (up to 25 mmHg is acceptable) when breathing room air.

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The PAO r P.02 gradient is normally ##BAD TAG##

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The PAO r P.0 2 gradient reflects the degree of right-to-left shunl. There normally is a small right-to-left shunt, which is reflected by a small P ,., 0 2 - P,02 gradient of5-15 mmHg.

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The P 1 CO r PAC0 2 gradient reflects dead- spacing. Normally, there is a small P, CO i-P"C02 grad ien t of2-10 mmHg, when breathing room ai r.

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The P ,., 0 2 -P,0 2 gradient in creases any time shunting increases

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he P 1 CO i- p "C02 gradienl also increases when deadspaci ng or shunting increases.

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~and the amount ofhemoglobi.!l are the two factors that determine the amount of oxygen carried by hemoglobin

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The flat portion of the oxyhemoglobin dissociation curve facilitates the loading of oxygen by the blood because, in the flat portion of this curve, large changes in the partial pressure of oxygen in arterial blood (P,0 2) produ ce only small changes in oxygen saturation (S, 0 2).

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The steep portion of the oxyhemoglobin dissociation curve facilitates unloading of oxygen at tissues because large amounts of oxygen are un- loaded from hemoglobin (large decrease in oxygen saturation) in re- sponse Lo a small change in the partial pressure of oxygen.

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When P,0 2 falls below 60 mmHg, large reductions in S,0 2 occur with small decreases in P.0 2 •

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The P 50 increases when the oxyhemoglobin dissociation curve shifts to the ri ght and decre!lse.~ when the oxyhemoglohin dissociation curve shifts to the left

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The oxyhemoglobin curve shifts to the left when PC0 2 decreases; this leftward shift occurs in pulmon ary capillaries as C01 is blown off; O, loading by he m oglobin is favored in pulmonary capillaries when the oxyhemoglobin dissociati on curve shifts left .

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The oxyhemog l obin curve shifts to the right when PC0 2 increases; this right ward shift, which occurs as blood flows through capillaries of the tissues, is important because more 02 is released from Hgb; unloading of 0 2 is favored with a r ightward sh ift in the oxyhemoglobin dissociation curve, so the tissues get more 02.

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(l) Decreased temperature, (2) decreased W concentration (increased pH), (3) decreased partial pressure of C02, (4) decreased 2, 3-DPG, (5) presence of fetal hemoglobin, (6) presence of carboxyhemoglobin, and (7) presence of methemoglobin

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(I) Increased temperature, (2) increased H' concentration (decreased pH). (3) increased partial pressure of C02, (4) increased 2,3-DPG, and (5) sickle cell disease. In general, increased metabolism promotes a rightward shift of the oxyhemoglo b in curve, facilitating unloading of oxygen at the tiss u es.

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The shift in the oxyhemoglobin dissociation curve caused by carbon diox - ide entering or leaving the blood is the Bohr effect.

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increase in PC0 2 in systemic capilla r ies is partly responsible for shifting the oxyhemoglobin dissociation curve rightward, which facilitates the unloading of oxygen from hemoglobin.

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The decrease in PC02 in pulmo- nary capillaries, on the other hand, helps shift the O>,')'hemoglobin curve to the left, which facilitates the loading of oxygen on to h emoglobin.

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#digitalizacion #eni #normativa
IV.1 Las imágenes electrónicas aplicarán los formatos establecidos para ficheros de imagen en la Norma Técnica de Interoperabilidad de Catálogo de Estándares. IV.2 El nivel de resolución mínimo para imágenes electrónicas será de 200 píxeles por pulgada, tanto para imágenes obtenidas en blanco y negro, color o escala de grises. IV.3 La imagen electrónica será fiel al documento origen, para lo cual: a) Respetará la geometría del documento origen en tamaños y proporciones. b) No contendrá caracteres o gráficos que no figurasen en el documento origen. c) Su generación atenderá a lo establecido en el apartado V de esta norma

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#digitalizacion #eni #normativa
El nivel de resolución de 200 ppp (píxeles por pulgada) se establece en la NTI como un mínimo para garantizar que la imagen sea legible.

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#digitalizacion #eni #normativa
Una imagen fiel, con la integridad suficiente a efectos probatorios, de un documento papel es un conjunto de componentes digitales que representan el contenido y aspecto del documento original, así como las características o metadatos asociados que contribuyen a garantizar la fidelidad de la imagen que, en cualquier caso, vendría avalada por la firma electrónica correspondiente al proceso de digitalización. Por lo tanto, y según establece el epígrafe IV.3.b de la NTI, el proceso de digitalización debe respetar las proporciones del documento origen y no añadir caracteres o gráficos que no figurasen en el aquél. 36. La fidelidad de la imagen es interpretada de forma proporcional a las exigencias de fidelidad e integridad específicas de cada documento que serán establecidas por cada organización según la normativa de aplicación en cada caso. Estas exigencias, que pueden incluir tanto la criticidad de los documentos para una organización, su gestión de riesgos y la aplicación de regulaciones específicas, son generalmente establecidas mediante procesos de gestión documental.

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[unknown IMAGE 1696322424076]
Proceso de digitalización
#digitalizacion #eni #has-images #normativa

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[unknown IMAGE 1696325831948]
Metadatos complementarios en el proceso de digitalización
#digitalizacion #eni #has-images #normativa

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#digitalizacion #eni #normativa
Por lo tanto, tras seguir el procedimiento descrito de digitalización, el resultado de éste podría ser: i. Un documento electrónico digitalizado, fiable e íntegro, completamente conformado : si durante el proceso de digitalización se asignan, además de todos los metadatos mínimos obligatorios establecidos en la NTI de Documento Electrónico y en su caso los complementarios al proceso de digitalización, la firma/firmas al fichero imagen obtenido. ii. Un documento electrónico digitalizado pendiente de completar: cuando, por criterio de la organización, no se ha asociado al documento la firma electrónica correspondiente.

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[unknown IMAGE 1696331861260]
Estructura Contenido del Documento Electrónico
#documento-electronico #eni #has-images #normativa

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[unknown IMAGE 1696335269132]
Estructura Metadatos Documento Electrónico
#documento-electronico #eni #has-images #normativa

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[unknown IMAGE 1696338939148]
Estructura firmas Documento Electrónico
#documento-electronico #eni #has-images #normativa

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#transparencia
La LTBG tiene carácter básico y se apoya en el artículo 149.1.18ª de la Constitución como título competencial principal. Prácticamente casi toda su regulación tiene dicho carácter básico. Sólo se excluye del mismo la regulación del Portal de Transparencia de la Administración General del Estado, de las Unidades de Información de la propia AGE y el Consejo Estatal de Transparencia y Buen Gobierno. El resto tiene la condición de básico y es de obligado cumplimiento para las Comunidades Autónomas. La LTBG entró en vigor para la parte reguladora de la transparencia y el acceso a la información pública de una manera escalonada:

-El 10 de diciembre de 2014, tras un año desde el día siguiente al de su publicación en BOE.
-Los órganos de las Comunidades Autónomas y Entidades Locales dispusieron de un plazo máximo de dos años para adaptarse a las obligaciones contenidas
en la Ley, es decir hasta el 10 de diciembre de 2015

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#transparencia
Las leyes autonómicas de transparencia Las Comunidades Autónomas y las Entidades Locales no tuvieron una participación activa en el proceso de elaboración de la LTBG. No obstante, son sujetos principales en su desarrollo y aplicación. Todas las Comunidades Autónomas han optado por dotarse de una ley autonómica de transparencia o están próxima a su aprobación, a pesar de que el carácter básico de la LTBG les ha dejado un margen de decisión limitado. Sin embargo, las leyes autonómicas no se han limitado a regular aspectos organizativos o procedimentales sino que han optado por desarrollar con amplitud la ley básica estatal ampliando sus obligaciones y mejorándola sustancialmente en aquellos aspectos en los que era posible.

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#transparencia
Publicación, entrada en vigor y desarrollo reglamentario La Ley 1/2014, de 24 de junio, de Transparencia Pública de Andalucía (LTPA) Publicación en Boja: El 30 de junio de 2014. Entrada en vigor: 30 de junio de 2015, al año de su publicación. Esto supuso un adelanto en la adaptación de las obligaciones establecidas en la ley básica estatal, que como recordaremos permitía un plazo de adaptación que terminaba el 10 de diciembre de 2015. No obstante, dado que la LTPA es más exigente que la ley básica estatal, el legislador andaluz ha preferido dar un plazo más amplio para las entidades locales andaluzas, estableciendo que dispondrán de “un plazo máximo de dos años, desde la entrada en vigor de la Ley 19/2013, de 9 de diciembre, para adaptarse a las obligaciones contenidas en esta ley”. Desarrollo reglamentario: hasta la fecha se han aprobado dos normas que desarrollan lo dispuesto en la Ley: 1. El Decreto 434/2015, de 29 de septiembre, por el que se aprueban los Estatutos del Consejo de Transparencia y Protección de Datos de Andalucía. 2. El Decreto 289/2015, de 21 de julio, por el que se regula la organización administrativa en materia de transparencia pública en el ámbito de la Administración de la Junta de Andalucía y sus entidades instrumentales.

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#transparencia
La estructura de la LTPA es la siguiente: Título I. Disposiciones generales. Título II. La publicidad activa. Título III. El derecho de acceso a la información pública. Título IV. Fomento de la Transparencia. Título V. Organización. Título VI. Régimen sancionador. 7 Disposiciones adicionales. 2 Disposiciones transitorias. 5 Disposiciones finales

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#gestion-it
Las organizaciones pueden y deben realizar escucha activa en Internet, en dos vertientes: Una escucha micro, leyendo íntegramente y analizando, diariamente, los mensajes y opiniones que se vierten en la red sobre la organización, o como mínimo aquellos mensajes más significativos y los que van dirigidos directamente a la organización. Este tipo de escucha puede compararse a la revisión de los resúmenes de prensa, si bien tiene un alcance mayor dado que las características de la comunicación en Internet hacen que en muchas ocasiones sea necesario no sólo escuchar, sino también responder por el mismo medio por el que nos llega el mensaje, a veces tan sólo para agradecer el mensaje recibido, y otras veces para completar, matizar o aclarar la información dada. Una escucha macro, basada en el análisis estadístico o sistematizado de los miles o millones de conversaciones que se realizan en la red y que tienen relación con la organización. Esta escucha macro debe basarse en herramientas potentes que faciliten la captura de la información así como su clasificación y análisis.

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#gestion-it
El proceso de escucha activa incluye, según Steve A Furman, las siguientes actividades: Recoger datos: aprovechando la tecnología. Automatizando las comunicaciones y practicando escucha activa. Conectar: Relacionar la retroalimentación (feedback) recibida con la experiencia del usuario, y relacionar esto con el impacto en la organización. Informar: Convocar regularmente reuniones multifuncionales, informar de los hallazgos y realizar recomendaciones. Actuar: trasladar las recomendaciones a proyectos con valor para la organización.

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Transporter proteins have a unique gatekeeper function in controlling drug access to metabolizing enzymes and excretory pathways

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#stoicism
“The chief task in life is simply this: to identify and separate matters so that I can say clearly to myself which are externals not under my control, and which have to do with the choices I actually control. Where then do I look for good and evil? Not to uncontrollable externals, but within myself to the choices that are my own . . .” —EPICTETUS, DISCOURSES, 2.5.4–5

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#stoicism
L January 5th CLARIFY YOUR INTENTIONS “Let all your efforts be directed to something, let it keep that end in view. It’s not activity that disturbs people, but false conceptions of things that drive them mad.” —SENECA, ON TRANQUILITY OF MIND, 12.5 aw 29 of The 48 Laws of Power is: Plan All The Way To The End. Robert Greene writes, “By planning to the end you will not be overwhelmed by circumstances and you will know when to stop. Gently guide fortune and help determine the future by thinking far ahead.” The second habit in The 7 Habits of Highly Effective People is: begin with an end in mind. Having an end in mind is no guarantee that you’ll reach it—no Stoic would tolerate that assumption—but not having an end in mind is a guarantee you won’t. To the Stoics, oiêsis (false conceptions) are responsible not just for disturbances in the soul but for chaotic and dysfunctional lives and operations. When your efforts are not directed at a cause or a purpose, how will you know what to do day in and day out? How will you know what to say no to and what to say yes to? How will you know when you’ve had enough, when you’ve reached your goal, when you’ve gotten off track, if you’ve never defined what those things are? The answer is that you cannot. And so you are driven into failure—or worse, into madness by the oblivion of directionlessness.

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#stoicism
“A person who doesn’t know what the universe is, doesn’t know where they are. A person who doesn’t know their purpose in life doesn’t know who they are or what the universe is. A person who doesn’t know any one of these things doesn’t know why they are here. So what to make of people who seek or avoid the praise of those who have no knowledge of where or who they are?” —MARCUS AURELIUS, MEDITATIONS, 8.52

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#stoicism
January 7th SEVEN CLEAR FUNCTIONS OF THE MIND “The proper work of the mind is the exercise of choice, refusal, yearning, repulsion, preparation, purpose, and assent. What then can pollute and clog the mind’s proper functioning? Nothing but its own corrupt decisions.” —EPICTETUS, DISCOURSES, 4.11.6–7

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#stoicism
W January 8th SEEING OUR ADDICTIONS “We must give up many things to which we are addicted, considering them to be good. Otherwise, courage will vanish, which should continually test itself. Greatness of soul will be lost, which can’t stand out unless it disdains as petty what the mob regards as most desirable. —SENECA, MORAL LETTERS, 74.12b–13 hat we consider to be harmless indulgences can easily become full- blown addictions. We start with coffee in the morning, and soon enough we can’t start the day without it. We check our email because it’s part of our job, and soon enough we feel the phantom buzz of the phone in our pocket every few seconds. Soon enough, these harmless habits are running our lives. The little compulsions and drives we have not only chip away at our freedom and sovereignty, they cloud our clarity. We think we’re in control— but are we really? As one addict put it, addiction is when we’ve “lost the freedom to abstain.” Let us reclaim that freedom. What that addiction is for you can vary: Soda? Drugs? Complaining? Gossip? The Internet? Biting your nails? But you must reclaim the ability to abstain because within it is your clarity and self-control.

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#stoicism
“Some things are in our control, while others are not. We control our opinion, choice, desire, aversion, and, in a word, everything of our own doing. We don’t control our body, property, reputation, position, and, in a word, everything not of our own doing. Even more, the things in our control are by nature free, unhindered, and unobstructed, while those not in our control are weak, slavish, can be hindered, and are not our own.” —EPICTETUS, ENCHIRIDION, 1.1–2

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#draw #has-images

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#hipócrates
Aos muito velhos, quando lhes sobrevém essa doença, ela provoca, por essa razão, a morte ou a paralisia, ou seja, porque as veias se esvaziam, e o sangue é parco, rarefato e aquoso. Se, então, há fluxo abundante e for a época de inverno, o indivíduo morre. Pois o fluxo esgana e coagula o sangue, se ele sobrevém por ambos os lados.

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#hipócrates
De tudo isso somos passíveis a partir do cérebro, quando este não está saudável, porém torna-se mais quente do que sua natureza, ou mais frio, ou mais úmido, ou mais seco, ou sofre, contra a natureza, outra afecção que lhe é inabitual. Enlouquecemos devido à umidade

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#hipócrates
alguém considerar que esses temas são muito estratosféricos, se ele mudar de opinião, poderá aprender que a astronomia tem lugar na medicina, e não um lugar pequeno, mas realmente grande; pois as cavidades mudam nos homens de acordo com as estações do ano

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