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on 06-Jun-2021 (Sun)

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#Endocardite #Metabolomics #These #Thèse
In general, IE-producing strains of staphylococci and streptococci more actively aggregate platelets than do other bacteria that less frequently produce IE
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#Endocardite #Metabolomics #These #Thèse
Streptococcal exo- polysaccharide production inversely correlates with platelet adhesion while inhibiting aggregation, 145 indicating that these surface molecules may enhance endocarditis at some pathogenic steps but not at others.
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#Endocardite #Metabolomics #These #Thèse
Platelets also may play a role in host defense within the cardiac vegetation during IE. 153 It is underappreciated that platelets can actually phagocytose circulating staphylococci into engulfment vacuoles, in which the organism can persist. 154
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