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on 07-Mar-2025 (Fri)

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有许多 N2型ACh 受体(化学门控通道),终板膜以外的普通肌膜有电压 门控钠通道
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数 ACh 被突触后膜的乙酰胆碱酯酶(AChE) 水解 ttsx 动作电位传导相对不疲劳,但神经-肌接头信息 传递会疲劳(递质耗竭) 静息状态突触
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新斯的明或有机磷农药中毒→抑制胆碱酯酶→ACh 大量蓄积→肌束颤动等 N样症 状,心率减慢、针尖样瞳孔、大量出汗等 M样症状
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