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[unknown IMAGE 5009388997900] #dictionaries #has-images #immutable-key #python-for-data-science
A dictionary holds a combination of key value pairs. Here, the keys are fictitious student IDs and student names. This is something you might maintain for the students in a course. You can use this data structure to ask if a student ID is in the dictionary and you can look up a student by their student ID number. Speaking of lookup, dictionaries are also super fast at doing lookups, which is one of the many reasons people like using this data structure. In this example, we have a string key and a string value. The only restriction on types is that the key has to be immutable. Let's look at some more examples. Here we have a mapping of courses to the instructors who commonly teach that course at UCSD. Notice that the value here is actually a list. You could even have a value be another dictionary. Any object is fine as a value in a key value pair, and remember, everything in Python is an object.
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[unknown IMAGE 5037908430092] #grep #has-images #python-for-data-science #using-unix-in-jupyter
Now let's look for an occurrence of the word parchment in the file. As you might remember, the command they'll use for this is grep. Using the grep command will display all the lines that have the word parchment in it, at least once. So here we say !grep -i 'parchment' $filename so this should give us all the lines when I say shift enter in that line. So basically each of these lines have the word parchment somewhere in there.
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plaats



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rangschikking?



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vorm?



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oppervlak?



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HISTOPATHOLOGISCH ONDERZOEK

Afwijkingen in epidermis en basaalmembraan




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HISTOPATHOLOGISCH ONDERZOEK

Afwijkingen in de dermis 5




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HISTOPATHOLOGISCH ONDERZOEK

Afwijkingen in de subcutis 1




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URETHRITIS

Kliniek 3

Indeling 4

Verwekkers 3




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GONORROE

Eigenschappen

Kliniek 2

Diagnostiek 3

Behandeling 3

Complicaties 4




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CHLAMYDIA TRACHOMATIS

Behandeling 3

Answer

▪ azitromycine 4x 250mg per os, eenmalig

▪ doxycycline 2dd 100mg per os, 7 dagen

▪ erythromycine 4dd 500mg per os, 7 dagen, in geval van verd. zwangerschap


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ULCUS MOLLE

Eigenschappen

Kliniek

Diagnostiek

Behandeling 4




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SYFILIS

Eigenschappen

Epidemiologie




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SYFILIS

Kliniek 7




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SYFILIS

Diagnostiek 3

Behandeling 2

Complicaties 1




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SCABIËS

Behandeling 6




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SCHAAMLUIS (PHTIRIASIS)

Eigenschappen

Etiologie/pathogenese




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SCHAAMLUIS (PHTIRIASIS)

Kliniek 4




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SCHAAMLUIS (PHTIRIASIS)

Diagnostiek 2

Behandeling 2




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HERPES GENITALIS

Eigenschappen




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BACTERIËLE VAGINOSE (GARDNERELLA VAGINALIS-VAGINITIS)

Eigenschappen

Epidemiologie




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BACTERIËLE VAGINOSE (GARDNERELLA VAGINALIS-VAGINITIS)

Kliniek 4




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BACTERIËLE VAGINOSE (GARDNERELLA VAGINALIS-VAGINITIS)

Diagnostiek 1

Behandeling 3




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CANDIDA VAGINITIS

Eigenschappen 5

Epidemiologie 2




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CANDIDA VAGINITIS

Kliniek 3

Diagnostiek 2




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CANDIDA VAGINITIS

Behandeling 3




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TRICHOMONIASIS

Eigenschappen

Epidemiologie




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ORTHO-ERGISCHE CONTACTDERMATITIS

Etiologie/Pathogenese 7




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ORTHO-ERGISCHE CONTACTDERMATITIS

Kliniek 2

Diagnostiek 2




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ORTHO-ERGISCHE CONTACTDERMATITIS

Behandeling 2




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ACROVESICULEUS ECZEEM

Epidemiologie 2




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ACROVESICULEUS ECZEEM

  • Kliniek 4
  • Diagnostiek 2



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ACROVESICULEUS ECZEEM

Behandeling 2




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NUMMULAIR ECZEEM

  • Epidemiologie 1
  • Etiologie/Pathogenese 3



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NUMMULAIR ECZEEM

  • Kliniek 4



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NUMMULAIR ECZEEM

  • Diagnostiek 3
  • Behandeling 1



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SEBORROISCH ECZEEM

  • Epidemiologie 3
  • Etiologie/Pathogenese 3



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SEBORROISCH ECZEEM

  • Kliniek 2



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SEBORROISCH ECZEEM

  • Diagnostiek 2
  • Behandeling 3



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CONSTITUTIONEEL ECZEEM

  • Epidemiologie 2



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CONSTITUTIONEEL ECZEEM

  • Etiologie/Pathogenese
    • Familiair
    • Allergische factoren 5
    • Niet allergische factoren 4



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CONSTITUTIONEEL ECZEEM

  • Kliniek
    • Zuigelingen 2
    • Peuterleeftijd 6
    • Reactievormen 4



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CONSTITUTIONEEL ECZEEM

  • Diagnostiek 4



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CONSTITUTIONEEL ECZEEM

  • Behandeling 4



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HYPOSTATISCH ECZEEM

  • Kliniek 12



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HYPOSTATISCH ECZEEM

  • Diagnostiek 2



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HYPOSTATISCH ECZEEM

  • Behandeling 2



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PEMPHIGUS

  • Epidemiologie 2



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PEMPHIGUS

Etiologie/Pathogenese 5




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PEMPHIGUS

  • Diagnostiek 4




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PEMPHIGUS

  • Behandeling 2



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BULLOUS PEMPHIGOID OF PARAPEMPHIGUS

  • Epidemiologie 3



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BULLOUS PEMPHIGOID OF PARAPEMPHIGUS

  • Etiologie/Pathogenese 3



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BULLOUS PEMPHIGOID OF PARAPEMPHIGUS

  • Kliniek 5



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BULLOUS PEMPHIGOID OF PARAPEMPHIGUS

  • Diagnostiek 4



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BULLOUS PEMPHIGOID OF PARAPEMPHIGUS

  • Behandeling 5



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DERMATITIS HERPETIFORMIS

  • Epidemiologie 2
  • Etiologie/Pathogenese 3



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DERMATITIS HERPETIFORMIS

  • Epidemiologie 2
  • Etiologie/Pathogenese 3




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DERMATITIS HERPETIFORMIS

  • Kliniek 8



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Diagnostiek

  • Histopathologie: micro-abcessen in dermale papillen (neutrofielen granulocyten). Soms ook veel eos (moeilijk te diff met parapemphigus).
  • Immunohistochemie van huidbiopt: granulaire depositie IgA, met voorkeur in de dermale papillen. Ook C3 aantoonbaar.
  • Jodiumhoudend plakproef (KJ-plakproef)
  • Jejunumvlokkenatrofie 90% (zelden darmklachten)
  • Uitsluiten bij inactieve dermatitis herpetiformis: prurgo, scabies en constitutioneel eczeem.
statusnot read reprioritisations
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Diagnostiek

  • [...]
Answer
Histopathologie: micro-abcessen in dermale papillen (neutrofielen granulocyten). Soms ook veel eos (moeilijk te diff met parapemphigus).Immunohistochemie van huidbiopt: granulaire depositie IgA, met voorkeur in de dermale papillen. Ook C3 aantoonbaar. Jodiumhoudend plakproef (KJ-plakproef)Jejunumvlokkenatrofie 90% (zelden darmklachten)Uitsluiten bij inactieve dermatitis herpetiformis: prurgo, scabies en constitutioneel eczeem.

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Diagnostiek Histopathologie: micro-abcessen in dermale papillen (neutrofielen granulocyten). Soms ook veel eos (moeilijk te diff met parapemphigus). Immunohistochemie van huidbiopt: granulaire depositie IgA, met voorkeur in de dermale papillen. Ook C3 aantoonbaar. Jodiumhoudend plakproef (KJ-plakproef) Jejunumvlokkenatrofie 90% (zelden darmklachten) Uitsluiten bij inactieve dermatitis herpetiformis: prurgo, scabies en constitutioneel eczeem.

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DERMATITIS HERPETIFORMIS

  • Behandeling 2



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PITYRIASIS ROSEA

  • Eigenschappen
  • Etiologie
  • Epidemiologie



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PITYRIASIS ROSEA

  • Kliniek 4



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PITYRIASIS ROSEA

  • Behandeling 2



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ERYTHEMA EXSUDATIVUM MULTIFORME (MINOR)

  • Eigenschappen
  • Etiologie/pathogenese



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ERYTHEMA EXSUDATIVUM MULTIFORME (MINOR)

  • Kliniek 5



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ERYTHEMA EXSUDATIVUM MULTIFORME (MINOR)

DD Andere dermatosen:

Answer
  • Parapemphigus,
  • dermatitis herpetiformis,
  • lupus erythematoses, vasculitis,
  • syndroom van sweet,
  • M. Kawasaki,
  • toxicodermie en virale exanthemen,
  • daarnaast urticaria.

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ERYTHEMA EXSUDATIVUM MULTIFORME (MINOR)

Diagnostische criteria: 7

Answer
  • Acuut,
  • self limited of episodisch
  • Duur episode max 4 weken
  • Efflorescenties symmetrisch en niet vluchtig
  • Minstens enkele schietscijflaesies
  • Slijmvliesafwijkingen afwezig of oraal
  • Geen aanwijzingen voor leukocytoelastische vasculitis

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ERYTHEMA EXSUDATIVUM MULTIFORME (MINOR)

  • behandeling 3
Answer
  • Symptomatisch met antihystaminica.
  • Bij ernstige gevallen valaciclovir of famciclovir, eventueel ook profylactisch.
  • Geen corticosteroiden, deze verhogen het aantal recidieven.

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MAJOR (STEVENS-JOHNSON SYNDROOM) (20%)

  • Epidemiologie 3
  • Etiologie/pathogenese 2



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MAJOR (STEVENS-JOHNSON SYNDROOM) (20%)

Kliniek 7

Answer
  • Prodromen BOLWI, koorts, hoesten, hoofdpijn, rhinitis en keelpijn, braken diaarre en algehele malaise.
    • Periode duurt 1-14 dagen.
  • Daarna abrupt efflorescenties zoals bij de minorvorm met snelle uitbreiding, blaasvorming en epidermale necrose.
    • Duurt 1-7 dagen. Tenminste 2 slijmvlieslocalisaties (mond, conjunctiva, genitalia en anus).
  • Andere symptomen en complicaties zijn artritis, blindheid, stricturen etc.
  • Soms secundaire infecties en sepsis.
  • Totaal aangedane lichaamsoppervlak: 10-30%

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DD bij MAJOR (STEVENS-JOHNSON SYNDROOM) (20%)

3

Answer
  • Toxische epidermale necrolyse (fulminanter begin),
  • staphylococcal scalded skin syndrome (S. Aureus),
  • graft vs host ziekte

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MAJOR (STEVENS-JOHNSON SYNDROOM) (20%)

Behandeling 2

Answer
  • Hoge mortaliteit door sepsis, pneumonie en verstoorde electrolyten en vochtbalans.
  • Multidisciplinair behandelen, eventueel hoge dosis cortico’s.

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TOXISCHE EPIDERMALE NECROLYSIS (TEN)

  • Epidemiologie 1
  • Etiologie/Pathogenese 3



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TOXISCHE EPIDERMALE NECROLYSIS (TEN)

  • Kliniek 4



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TOXISCHE EPIDERMALE NECROLYSIS (TEN)

  • Diagnostiek 1
  • Behandeling 5



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PSORIASIS

  • Epidemiologie 3



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PSORIASIS

  • Etiologie/Pathogenese 5



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  • PSORIASIS Kliniek
  • ▪ Huidmanifestaties: scherp begrensde erythematosquameuze plaques
  • ▪ Verschillende vormen:
    • Plaquepsoriasis: beperkt tot enkele plaques Bij chronische plaquepsoriasis samenvloeien van suameuze papels waardoor plaques ontstaan met zilverkleurige schilfering die bij krabben vervloeid als kaarsvet. Voorkeurslocalisatie strekzijde ellebogen en knieën, behaarde hoofd en regio sacralis. Symmetrisch, meestal zonder jeuk. Remissieperioden tot vijf jaar of langer. -
    • Psoriasis guttata: gedissemineerd met erythematosquameuze papels Is de vorm waarin psoriasis zich meestal presenteert, bij kinderen spontane remissie in weken, volwassenen chronisch. -
    • Erytrodermatische psoriasis: gehele huid aangetast Erytrodermie waarbij aantasting interne milieu met dehydratie en nierinsufficiëntie tot gevolg. - Pustuleuze psoriasis: Pustels waarna desquamatie. Pat. is ziek, heeft hoge koorts, herstellend na enkele weken en recidiverend in maanden.
  • ▪ 10-55% heeft nagelafwijkingen (putjes, olievlekfenomeen, distale onycholysis, subunguale hyperkeratose)
  • ▪ Ongeveer 7% heeft last van psoriasis arthropatica, serologisch onderzoek naar reuma moet negatief zijn
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Flashcard 5039440661772

Question
  • PSORIASIS Kliniek
  • ▪ Huidmanifestaties: scherp begrensde erythematosquameuze plaques
  • ▪ Verschillende vormen:
    • [...]: beperkt tot enkele plaques Bij chronische plaquepsoriasis samenvloeien van suameuze papels waardoor plaques ontstaan met zilverkleurige schilfering die bij krabben vervloeid als kaarsvet. Voorkeurslocalisatie strekzijde ellebogen en knieën, behaarde hoofd en regio sacralis. Symmetrisch, meestal zonder jeuk. Remissieperioden tot vijf jaar of langer. -
    • [...] : gedissemineerd met erythematosquameuze papels Is de vorm waarin psoriasis zich meestal presenteert, bij kinderen spontane remissie in weken, volwassenen chronisch. -
    • [...] : gehele huid aangetast Erytrodermie waarbij aantasting interne milieu met dehydratie en nierinsufficiëntie tot gevolg. - Pustuleuze psoriasis: Pustels waarna desquamatie. Pat. is ziek, heeft hoge koorts, herstellend na enkele weken en recidiverend in maanden.
  • ▪ 10-55% heeft nagelafwijkingen (putjes, olievlekfenomeen, distale onycholysis, subunguale hyperkeratose)
  • ▪ Ongeveer 7% heeft last van psoriasis arthropatica, serologisch onderzoek naar reuma moet negatief zijn
Answer
Plaquepsoriasis

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PSORIASIS Kliniek ▪ Huidmanifestaties: scherp begrensde erythematosquameuze plaques ▪ Verschillende vormen: Plaquepsoriasis: beperkt tot enkele plaques Bij chronische plaquepsoriasis samenvloeien van suameuze papels waardoor plaques ontstaan met zilverkleurige schilfering die bij krabben vervloeid als kaarsv

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Flashcard 5039443021068

Question
  • PSORIASIS Kliniek
  • ▪ Huidmanifestaties: scherp begrensde erythematosquameuze plaques
  • ▪ Verschillende vormen:
    • Plaquepsoriasis: [...]
    • Psoriasis guttata: gedissemineerd met erythematosquameuze papels Is de vorm waarin psoriasis zich meestal presenteert, bij kinderen spontane remissie in weken, volwassenen chronisch. -
    • Erytrodermatische psoriasis: gehele huid aangetast Erytrodermie waarbij aantasting interne milieu met dehydratie en nierinsufficiëntie tot gevolg. - Pustuleuze psoriasis: Pustels waarna desquamatie. Pat. is ziek, heeft hoge koorts, herstellend na enkele weken en recidiverend in maanden.
  • ▪ 10-55% heeft nagelafwijkingen (putjes, olievlekfenomeen, distale onycholysis, subunguale hyperkeratose)
  • ▪ Ongeveer 7% heeft last van psoriasis arthropatica, serologisch onderzoek naar reuma moet negatief zijn
Answer
beperkt tot enkele plaques Bij chronische plaquepsoriasis samenvloeien van suameuze papels waardoor plaques ontstaan met zilverkleurige schilfering die bij krabben vervloeid als kaarsvet. Voorkeurslocalisatie strekzijde ellebogen en knieën, behaarde hoofd en regio sacralis. Symmetrisch, meestal zonder jeuk. Remissieperioden tot vijf jaar of langer. -

statusnot learnedmeasured difficulty37% [default]last interval [days]               
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PSORIASIS Kliniek ▪ Huidmanifestaties: scherp begrensde erythematosquameuze plaques ▪ Verschillende vormen: Plaquepsoriasis: beperkt tot enkele plaques Bij chronische plaquepsoriasis samenvloeien van suameuze papels waardoor plaques ontstaan met zilverkleurige schilfering die bij krabben vervloeid als kaarsvet. Voorkeurslocalisatie strekzijde ellebogen en knieën, behaarde hoofd en regio sacralis. Symmetrisch, meestal zonder jeuk. Remissieperioden tot vijf jaar of langer. - Psoriasis guttata: gedissemineerd met erythematosquameuze papels Is de vorm waarin psoriasis zich meestal presenteert, bij kinderen spontane remissie in weken, volwassenen chronisch. -

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Flashcard 5039444593932

Question
  • PSORIASIS Kliniek
  • ▪ Huidmanifestaties: scherp begrensde erythematosquameuze plaques
  • ▪ Verschillende vormen:
    • Plaquepsoriasis: beperkt tot enkele plaques Bij chronische plaquepsoriasis samenvloeien van suameuze papels waardoor plaques ontstaan met zilverkleurige schilfering die bij krabben vervloeid als kaarsvet. Voorkeurslocalisatie strekzijde ellebogen en knieën, behaarde hoofd en regio sacralis. Symmetrisch, meestal zonder jeuk. Remissieperioden tot vijf jaar of langer. -
    • Psoriasis guttata: [...]
    • Erytrodermatische psoriasis: gehele huid aangetast Erytrodermie waarbij aantasting interne milieu met dehydratie en nierinsufficiëntie tot gevolg. - Pustuleuze psoriasis: Pustels waarna desquamatie. Pat. is ziek, heeft hoge koorts, herstellend na enkele weken en recidiverend in maanden.
  • ▪ 10-55% heeft nagelafwijkingen (putjes, olievlekfenomeen, distale onycholysis, subunguale hyperkeratose)
  • ▪ Ongeveer 7% heeft last van psoriasis arthropatica, serologisch onderzoek naar reuma moet negatief zijn
Answer
gedissemineerd met erythematosquameuze papels Is de vorm waarin psoriasis zich meestal presenteert, bij kinderen spontane remissie in weken, volwassenen chronisch. -

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kaarsvet. Voorkeurslocalisatie strekzijde ellebogen en knieën, behaarde hoofd en regio sacralis. Symmetrisch, meestal zonder jeuk. Remissieperioden tot vijf jaar of langer. - Psoriasis guttata: <span>gedissemineerd met erythematosquameuze papels Is de vorm waarin psoriasis zich meestal presenteert, bij kinderen spontane remissie in weken, volwassenen chronisch. - Erytrodermatische psoriasis: gehele huid aangetast Erytrodermie waarbij aantasting interne milieu met dehydratie en nierinsufficiëntie tot gevolg. - Pustuleuze psoriasis: Pustels waarna

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Flashcard 5039446166796

Question
  • PSORIASIS Kliniek
  • ▪ Huidmanifestaties: scherp begrensde erythematosquameuze plaques
  • ▪ Verschillende vormen:
    • Plaquepsoriasis: beperkt tot enkele plaques Bij chronische plaquepsoriasis samenvloeien van suameuze papels waardoor plaques ontstaan met zilverkleurige schilfering die bij krabben vervloeid als kaarsvet. Voorkeurslocalisatie strekzijde ellebogen en knieën, behaarde hoofd en regio sacralis. Symmetrisch, meestal zonder jeuk. Remissieperioden tot vijf jaar of langer. -
    • Psoriasis guttata: gedissemineerd met erythematosquameuze papels Is de vorm waarin psoriasis zich meestal presenteert, bij kinderen spontane remissie in weken, volwassenen chronisch. -
    • Erytrodermatische psoriasis: [...]
  • ▪ 10-55% heeft nagelafwijkingen (putjes, olievlekfenomeen, distale onycholysis, subunguale hyperkeratose)
  • ▪ Ongeveer 7% heeft last van psoriasis arthropatica, serologisch onderzoek naar reuma moet negatief zijn
Answer
gehele huid aangetast Erytrodermie waarbij aantasting interne milieu met dehydratie en nierinsufficiëntie tot gevolg. - Pustuleuze psoriasis: Pustels waarna desquamatie. Pat. is ziek, heeft hoge koorts, herstellend na enkele weken en recidiverend in maanden.

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edissemineerd met erythematosquameuze papels Is de vorm waarin psoriasis zich meestal presenteert, bij kinderen spontane remissie in weken, volwassenen chronisch. - Erytrodermatische psoriasis: <span>gehele huid aangetast Erytrodermie waarbij aantasting interne milieu met dehydratie en nierinsufficiëntie tot gevolg. - Pustuleuze psoriasis: Pustels waarna desquamatie. Pat. is ziek, heeft hoge koorts, herstellend na enkele weken en recidiverend in maanden. ▪ 10-55% heeft nagelafwijkingen (putjes, olievlekfenomeen, distale onycholysis, subunguale hyperkeratose) ▪ Ongeveer 7% heeft last van psoriasis arthropatica, serologisch onderzoek naar

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PSORIASIS DD



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PSORIASIS

  • Diagnostiek 2



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Behandeling PSORIASIS

  • Lokale behandeling:
    • - Actief vitamine D3 (calcipotriolzalf), vergelijkbaar met corticosteroïden klasse III-IV, bijw. hypercalciëmie
    • - Lokale corticosteroïden (klasse III-IV), dagelijks of wekelijks, bijw. bijniersuppressie
    • - Teer (ditranol) lokale inductie van vrije radicalen, licht tintelend effect wordt nagestreefd, bijw. vies
    • - Fototherapie met UV-B 311 nm, kuren 2-3 maanden twee keer per week
  • PUVA-therapie (psoraleen + UV-A) bij hoge expositie verhoogd risico huidkanker, erg effectief
  • Systemische behandeling:
    • - Vitamine-A-zuurderivaten (acitretin) bij pustuleuze en erytrodermatische vorm of i.c.m. lichttherapie bij overige vormen, bijw. verhoogde leverfuncties/cholesterol, osteofytvorming, anticonceptie tot twee jaar na behandeling absoluut noodzakelijk
    • - Methotrexaat zeer effectief, gereserveerd voor therapieresistente en ernstige vormen, alcoholverbod
    • - Cyclosporine A bij pustuleuze en erytrothematosquameuze vormen, bijw. hypertensie, nefrotoxiciteit en immunosuppressie
  • Experimenteel:
    • - Fumaarzuurderivaten, vit. D3 derivaten, cytochroom P450 remmers, immunomodulerende stoffen
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Flashcard 5039457701132

Question

Behandeling PSORIASIS

  • [...]:
    • - Actief vitamine D3 (calcipotriolzalf), vergelijkbaar met corticosteroïden klasse III-IV, bijw. hypercalciëmie
    • - Lokale corticosteroïden (klasse III-IV), dagelijks of wekelijks, bijw. bijniersuppressie
    • - Teer (ditranol) lokale inductie van vrije radicalen, licht tintelend effect wordt nagestreefd, bijw. vies
    • - Fototherapie met UV-B 311 nm, kuren 2-3 maanden twee keer per week
  • [...] (psoraleen + UV-A) bij hoge expositie verhoogd risico huidkanker, erg effectief
  • [...] :
    • - Vitamine-A-zuurderivaten (acitretin) bij pustuleuze en erytrodermatische vorm of i.c.m. lichttherapie bij overige vormen, bijw. verhoogde leverfuncties/cholesterol, osteofytvorming, anticonceptie tot twee jaar na behandeling absoluut noodzakelijk
    • - Methotrexaat zeer effectief, gereserveerd voor therapieresistente en ernstige vormen, alcoholverbod
    • - Cyclosporine A bij pustuleuze en erytrothematosquameuze vormen, bijw. hypertensie, nefrotoxiciteit en immunosuppressie
  • [...] :
    • - Fumaarzuurderivaten, vit. D3 derivaten, cytochroom P450 remmers, immunomodulerende stoffen
Answer
Lokale behandeling

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Behandeling PSORIASIS Lokale behandeling: - Actief vitamine D3 (calcipotriolzalf), vergelijkbaar met corticosteroïden klasse III-IV, bijw. hypercalciëmie - Lokale corticosteroïden (klasse III-IV), dagelijks of wekelijks, bijw.

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Behandeling PSORIASIS

  • Lokale behandeling:
    • [...]
  • PUVA-therapie (psoraleen + UV-A) bij hoge expositie verhoogd risico huidkanker, erg effectief
  • Systemische behandeling:
    • - Vitamine-A-zuurderivaten (acitretin) bij pustuleuze en erytrodermatische vorm of i.c.m. lichttherapie bij overige vormen, bijw. verhoogde leverfuncties/cholesterol, osteofytvorming, anticonceptie tot twee jaar na behandeling absoluut noodzakelijk
    • - Methotrexaat zeer effectief, gereserveerd voor therapieresistente en ernstige vormen, alcoholverbod
    • - Cyclosporine A bij pustuleuze en erytrothematosquameuze vormen, bijw. hypertensie, nefrotoxiciteit en immunosuppressie
  • Experimenteel:
    • - Fumaarzuurderivaten, vit. D3 derivaten, cytochroom P450 remmers, immunomodulerende stoffen
Answer
- Actief vitamine D3 (calcipotriolzalf), vergelijkbaar met corticosteroïden klasse III-IV, bijw. hypercalciëmie- Lokale corticosteroïden (klasse III-IV), dagelijks of wekelijks, bijw. bijniersuppressie- Teer (ditranol) lokale inductie van vrije radicalen, licht tintelend effect wordt nagestreefd, bijw. vies- Fototherapie met UV-B 311 nm, kuren 2-3 maanden twee keer per week

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Behandeling PSORIASIS Lokale behandeling: - Actief vitamine D3 (calcipotriolzalf), vergelijkbaar met corticosteroïden klasse III-IV, bijw. hypercalciëmie - Lokale corticosteroïden (klasse III-IV), dagelijks of wekelijks, bijw. bijniersuppressie - Teer (ditranol) lokale inductie van vrije radicalen, licht tintelend effect wordt nagestreefd, bijw. vies - Fototherapie met UV-B 311 nm, kuren 2-3 maanden twee keer per week PUVA-therapie (psoraleen + UV-A) bij hoge expositie verhoogd risico huidkanker, erg effectief Systemische behandeling: - Vitamine-A-zuurderivaten (acitretin) bij pustuleuze en erytroder

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Flashcard 5039461633292

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Behandeling PSORIASIS

  • Lokale behandeling:
    • - Actief vitamine D3 (calcipotriolzalf), vergelijkbaar met corticosteroïden klasse III-IV, bijw. hypercalciëmie
    • - Lokale corticosteroïden (klasse III-IV), dagelijks of wekelijks, bijw. bijniersuppressie
    • - Teer (ditranol) lokale inductie van vrije radicalen, licht tintelend effect wordt nagestreefd, bijw. vies
    • - Fototherapie met UV-B 311 nm, kuren 2-3 maanden twee keer per week
  • PUVA-therapie [...]
  • Systemische behandeling:
    • - Vitamine-A-zuurderivaten (acitretin) bij pustuleuze en erytrodermatische vorm of i.c.m. lichttherapie bij overige vormen, bijw. verhoogde leverfuncties/cholesterol, osteofytvorming, anticonceptie tot twee jaar na behandeling absoluut noodzakelijk
    • - Methotrexaat zeer effectief, gereserveerd voor therapieresistente en ernstige vormen, alcoholverbod
    • - Cyclosporine A bij pustuleuze en erytrothematosquameuze vormen, bijw. hypertensie, nefrotoxiciteit en immunosuppressie
  • Experimenteel:
    • - Fumaarzuurderivaten, vit. D3 derivaten, cytochroom P450 remmers, immunomodulerende stoffen
Answer
(psoraleen + UV-A) bij hoge expositie verhoogd risico huidkanker, erg effectief

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ie - Teer (ditranol) lokale inductie van vrije radicalen, licht tintelend effect wordt nagestreefd, bijw. vies - Fototherapie met UV-B 311 nm, kuren 2-3 maanden twee keer per week PUVA-therapie <span>(psoraleen + UV-A) bij hoge expositie verhoogd risico huidkanker, erg effectief Systemische behandeling: - Vitamine-A-zuurderivaten (acitretin) bij pustuleuze en erytrodermatische vorm of i.c.m. lichttherapie bij overige vormen, bijw. verhoogde leverfuncties/choles

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Behandeling PSORIASIS

  • Lokale behandeling:
    • - Actief vitamine D3 (calcipotriolzalf), vergelijkbaar met corticosteroïden klasse III-IV, bijw. hypercalciëmie
    • - Lokale corticosteroïden (klasse III-IV), dagelijks of wekelijks, bijw. bijniersuppressie
    • - Teer (ditranol) lokale inductie van vrije radicalen, licht tintelend effect wordt nagestreefd, bijw. vies
    • - Fototherapie met UV-B 311 nm, kuren 2-3 maanden twee keer per week
  • PUVA-therapie (psoraleen + UV-A) bij hoge expositie verhoogd risico huidkanker, erg effectief
  • Systemische behandeling:
  • [...]xperimenteel:
    • - Fumaarzuurderivaten, vit. D3 derivaten, cytochroom P450 remmers, immunomodulerende stoffen
Answer
- Vitamine-A-zuurderivaten (acitretin) bij pustuleuze en erytrodermatische vorm of i.c.m. lichttherapie bij overige vormen, bijw. verhoogde leverfuncties/cholesterol, osteofytvorming, anticonceptie tot twee jaar na behandeling absoluut noodzakelijk- Methotrexaat zeer effectief, gereserveerd voor therapieresistente en ernstige vormen, alcoholverbod- Cyclosporine A bij pustuleuze en erytrothematosquameuze vormen, bijw. hypertensie, nefrotoxiciteit en immunosuppressie

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vies - Fototherapie met UV-B 311 nm, kuren 2-3 maanden twee keer per week PUVA-therapie (psoraleen + UV-A) bij hoge expositie verhoogd risico huidkanker, erg effectief Systemische behandeling: <span>- Vitamine-A-zuurderivaten (acitretin) bij pustuleuze en erytrodermatische vorm of i.c.m. lichttherapie bij overige vormen, bijw. verhoogde leverfuncties/cholesterol, osteofytvorming, anticonceptie tot twee jaar na behandeling absoluut noodzakelijk - Methotrexaat zeer effectief, gereserveerd voor therapieresistente en ernstige vormen, alcoholverbod - Cyclosporine A bij pustuleuze en erytrothematosquameuze vormen, bijw. hypertensie, nefrotoxiciteit en immunosuppressie Experimenteel: - Fumaarzuurderivaten, vit. D3 derivaten, cytochroom P450 remmers, immunomodulerende stoffen <span>

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Behandeling PSORIASIS

  • Lokale behandeling:
    • - Actief vitamine D3 (calcipotriolzalf), vergelijkbaar met corticosteroïden klasse III-IV, bijw. hypercalciëmie
    • - Lokale corticosteroïden (klasse III-IV), dagelijks of wekelijks, bijw. bijniersuppressie
    • - Teer (ditranol) lokale inductie van vrije radicalen, licht tintelend effect wordt nagestreefd, bijw. vies
    • - Fototherapie met UV-B 311 nm, kuren 2-3 maanden twee keer per week
  • PUVA-therapie (psoraleen + UV-A) bij hoge expositie verhoogd risico huidkanker, erg effectief
  • Systemische behandeling:
    • - Vitamine-A-zuurderivaten (acitretin) bij pustuleuze en erytrodermatische vorm of i.c.m. lichttherapie bij overige vormen, bijw. verhoogde leverfuncties/cholesterol, osteofytvorming, anticonceptie tot twee jaar na behandeling absoluut noodzakelijk
    • - Methotrexaat zeer effectief, gereserveerd voor therapieresistente en ernstige vormen, alcoholverbod
    • - Cyclosporine A bij pustuleuze en erytrothematosquameuze vormen, bijw. hypertensie, nefrotoxiciteit en immunosuppressie
  • Experimenteel:
    • [...]
Answer
- Fumaarzuurderivaten, vit. D3 derivaten, cytochroom P450 remmers, immunomodulerende stoffen

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voor therapieresistente en ernstige vormen, alcoholverbod - Cyclosporine A bij pustuleuze en erytrothematosquameuze vormen, bijw. hypertensie, nefrotoxiciteit en immunosuppressie Experimenteel: <span>- Fumaarzuurderivaten, vit. D3 derivaten, cytochroom P450 remmers, immunomodulerende stoffen <span>

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LICHEN RUBER PLANUS

  • Epidemiologie 3
  • Etiologie 1



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LICHEN RUBER PLANUS

  • Pathogenese 2



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LICHEN RUBER PLANUS

  • Kliniek 5



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LICHEN RUBER PLANUS

  • Behandeling 3



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FOLLICULITIS

  • Pathogenese 2



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FOLLICULITIS

  • Kliniek 11

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FOLLICULITIS

  • Behandeling 2



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CUTANE LUPUS ERYTHEMATODES

  • Epidemiologie 2
  • Pathogenese 3



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CUTANE LUPUS ERYTHEMATODES Kliniek

  • ▪ remissies en exacerbaties
  • ▪ Chronische discoïde LE
    • - Rode, discusvormige scherp begrensde gebieden, perifeer verhevenheid en centraal ingezonken
    • - Met name op gelaat, behaarde hoofd, romp en armen
    • - Erytheem, keratose, atrofie, teleangiëctasieën, hyper-/depigmentaties
  • ▪ Subacture cutane LE
    • - M.n. op aan licht blootgestelde huiddelen (gelaat, romp, extemiteiten) scherp begrensde polycyclische erythemateuze schilferende huidafwijkingen
  • ▪ Acute LE
    • - Ontstaat in uren/dagen
    • - Soms duidelijke provocerende factor (licht, medicatie, infectie)
    • - Geneest vaak snel
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CUTANE LUPUS ERYTHEMATODES Kliniek

  • ▪ remissies en exacerbaties
  • [...]
    • - Rode, discusvormige scherp begrensde gebieden, perifeer verhevenheid en centraal ingezonken
    • - Met name op gelaat, behaarde hoofd, romp en armen
    • - Erytheem, keratose, atrofie, teleangiëctasieën, hyper-/depigmentaties
  • [...]
    • - M.n. op aan licht blootgestelde huiddelen (gelaat, romp, extemiteiten) scherp begrensde polycyclische erythemateuze schilferende huidafwijkingen
  • [...]
    • - Ontstaat in uren/dagen
    • - Soms duidelijke provocerende factor (licht, medicatie, infectie)
    • - Geneest vaak snel
Answer

▪ Chronische discoïde LE


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CUTANE LUPUS ERYTHEMATODES Kliniek ▪ remissies en exacerbaties ▪ Chronische discoïde LE - Rode, discusvormige scherp begrensde gebieden, perifeer verhevenheid en centraal ingezonken - Met name op gelaat, behaarde hoofd, romp en armen - Erytheem, keratose, atrofie, teleangi

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CUTANE LUPUS ERYTHEMATODES Kliniek

  • ▪ remissies en exacerbaties
  • ▪ Chronische discoïde LE
    • [...]
  • ▪ Subacture cutane LE
    • - M.n. op aan licht blootgestelde huiddelen (gelaat, romp, extemiteiten) scherp begrensde polycyclische erythemateuze schilferende huidafwijkingen
  • ▪ Acute LE
    • - Ontstaat in uren/dagen
    • - Soms duidelijke provocerende factor (licht, medicatie, infectie)
    • - Geneest vaak snel
Answer
- Rode, discusvormige scherp begrensde gebieden, perifeer verhevenheid en centraal ingezonken- Met name op gelaat, behaarde hoofd, romp en armen- Erytheem, keratose, atrofie, teleangiëctasieën, hyper-/depigmentaties

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CUTANE LUPUS ERYTHEMATODES Kliniek ▪ remissies en exacerbaties ▪ Chronische discoïde LE - Rode, discusvormige scherp begrensde gebieden, perifeer verhevenheid en centraal ingezonken - Met name op gelaat, behaarde hoofd, romp en armen - Erytheem, keratose, atrofie, teleangiëctasieën, hyper-/depigmentaties ▪ Subacture cutane LE - M.n. op aan licht blootgestelde huiddelen (gelaat, romp, extemiteiten) scherp begrensde polycyclische erythemateuze schilferende huidafwijkingen ▪ Acute LE - Ont

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CUTANE LUPUS ERYTHEMATODES Kliniek

  • ▪ remissies en exacerbaties
  • ▪ Chronische discoïde LE
    • - Rode, discusvormige scherp begrensde gebieden, perifeer verhevenheid en centraal ingezonken
    • - Met name op gelaat, behaarde hoofd, romp en armen
    • - Erytheem, keratose, atrofie, teleangiëctasieën, hyper-/depigmentaties
  • ▪ Subacture cutane LE
    • - [...]
  • ▪ Acute LE
    • - Ontstaat in uren/dagen
    • - Soms duidelijke provocerende factor (licht, medicatie, infectie)
    • - Geneest vaak snel
Answer
M.n. op aan licht blootgestelde huiddelen (gelaat, romp, extemiteiten) scherp begrensde polycyclische erythemateuze schilferende huidafwijkingen

statusnot learnedmeasured difficulty37% [default]last interval [days]               
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perifeer verhevenheid en centraal ingezonken - Met name op gelaat, behaarde hoofd, romp en armen - Erytheem, keratose, atrofie, teleangiëctasieën, hyper-/depigmentaties ▪ Subacture cutane LE - <span>M.n. op aan licht blootgestelde huiddelen (gelaat, romp, extemiteiten) scherp begrensde polycyclische erythemateuze schilferende huidafwijkingen ▪ Acute LE - Ontstaat in uren/dagen - Soms duidelijke provocerende factor (licht, medicatie, infectie) - Geneest vaak snel <span>

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CUTANE LUPUS ERYTHEMATODES Kliniek

  • ▪ remissies en exacerbaties
  • ▪ Chronische discoïde LE
    • - Rode, discusvormige scherp begrensde gebieden, perifeer verhevenheid en centraal ingezonken
    • - Met name op gelaat, behaarde hoofd, romp en armen
    • - Erytheem, keratose, atrofie, teleangiëctasieën, hyper-/depigmentaties
  • ▪ Subacture cutane LE
    • - M.n. op aan licht blootgestelde huiddelen (gelaat, romp, extemiteiten) scherp begrensde polycyclische erythemateuze schilferende huidafwijkingen
  • ▪ Acute LE
    • [...]
Answer
- Ontstaat in uren/dagen- Soms duidelijke provocerende factor (licht, medicatie, infectie)- Geneest vaak snel

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epigmentaties ▪ Subacture cutane LE - M.n. op aan licht blootgestelde huiddelen (gelaat, romp, extemiteiten) scherp begrensde polycyclische erythemateuze schilferende huidafwijkingen ▪ Acute LE <span>- Ontstaat in uren/dagen - Soms duidelijke provocerende factor (licht, medicatie, infectie) - Geneest vaak snel <span>

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CUTANE LUPUS ERYTHEMATODES

  • Diagnostiek 3



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CUTANE LUPUS ERYTHEMATODES

  • Behandeling 3
  • Complicaties 1



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Diagnose SLE ?

  • Indien 4 manifestaties aanwezig zijn, niet noodzakelijkerwijs tegelijkertijd, is er sprake van SLE.
  • 9



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ULCUS CRURIS

  • Epidemiologie 3



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ULCUS CRURIS

  • kliniek 5



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ULCUS CRURIS

  • etoilogie 2
  • diagnostiek 4



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ULCUS CRURIS

  • behandeling 3



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SCLERODERMA CIRCUMSCRIPTUM

  • Epidemiologie 3
  • Etiologie/pathogenese 1



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SCLERODERMA CIRCUMSCRIPTUM Kliniek

  • ▪ Scleroderma morphea (sclerodermie en plaques)
    • - Op romp (soms gezicht/extremiteiten)
    • - Begin met niet-jeukende rode plekken
    • - Later bruine verkleuring en verharding
  • ▪ Scleroderma linearis
    • - Aan extremiteiten (soms halfzijdig over lichaam)
    • - Langgerekte sclerotische gebieden, met veel hyper-/depigmentatie
    • - Evt. ook fascie, spieren en bot betrokken
  • ▪ Sclerodermie en coup de sabre
    • - Op het voorhoofd, met aantasting schedelbot
    • - Kan uitbreiden naar gelaat en mond
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SCLERODERMA CIRCUMSCRIPTUM Kliniek

  • [...]
    • - Op romp (soms gezicht/extremiteiten)
    • - Begin met niet-jeukende rode plekken
    • - Later bruine verkleuring en verharding
  • [...]
    • - Aan extremiteiten (soms halfzijdig over lichaam)
    • - Langgerekte sclerotische gebieden, met veel hyper-/depigmentatie
    • - Evt. ook fascie, spieren en bot betrokken
  • [...]
    • - Op het voorhoofd, met aantasting schedelbot
    • - Kan uitbreiden naar gelaat en mond
Answer
Scleroderma morphea (sclerodermie en plaques)

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SCLERODERMA CIRCUMSCRIPTUM Kliniek ▪ Scleroderma morphea (sclerodermie en plaques) - Op romp (soms gezicht/extremiteiten) - Begin met niet-jeukende rode plekken - Later bruine verkleuring en verharding ▪ Scleroderma linearis - Aan extremiteiten (soms halfzijdig over l

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SCLERODERMA CIRCUMSCRIPTUM Kliniek

  • ▪ Scleroderma morphea (sclerodermie en plaques)
    • [...]
  • ▪ Scleroderma linearis
    • - Aan extremiteiten (soms halfzijdig over lichaam)
    • - Langgerekte sclerotische gebieden, met veel hyper-/depigmentatie
    • - Evt. ook fascie, spieren en bot betrokken
  • ▪ Sclerodermie en coup de sabre
    • - Op het voorhoofd, met aantasting schedelbot
    • - Kan uitbreiden naar gelaat en mond
Answer
- Op romp (soms gezicht/extremiteiten)- Begin met niet-jeukende rode plekken- Later bruine verkleuring en verharding

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SCLERODERMA CIRCUMSCRIPTUM Kliniek ▪ Scleroderma morphea (sclerodermie en plaques) - Op romp (soms gezicht/extremiteiten) - Begin met niet-jeukende rode plekken - Later bruine verkleuring en verharding ▪ Scleroderma linearis - Aan extremiteiten (soms halfzijdig over lichaam) - Langgerekte sclerotische gebieden, met veel hyper-/depigmentatie - Evt. ook fascie, spieren en bot betrokken

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SCLERODERMA CIRCUMSCRIPTUM Kliniek

  • ▪ Scleroderma morphea (sclerodermie en plaques)
    • - Op romp (soms gezicht/extremiteiten)
    • - Begin met niet-jeukende rode plekken
    • - Later bruine verkleuring en verharding
  • ▪ Scleroderma linearis
    • [...]
  • ▪ Sclerodermie en coup de sabre
    • - Op het voorhoofd, met aantasting schedelbot
    • - Kan uitbreiden naar gelaat en mond
Answer
- Aan extremiteiten (soms halfzijdig over lichaam)- Langgerekte sclerotische gebieden, met veel hyper-/depigmentatie- Evt. ook fascie, spieren en bot betrokken

statusnot learnedmeasured difficulty37% [default]last interval [days]               
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scheduled repetition interval               last repetition or drill

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iek ▪ Scleroderma morphea (sclerodermie en plaques) - Op romp (soms gezicht/extremiteiten) - Begin met niet-jeukende rode plekken - Later bruine verkleuring en verharding ▪ Scleroderma linearis <span>- Aan extremiteiten (soms halfzijdig over lichaam) - Langgerekte sclerotische gebieden, met veel hyper-/depigmentatie - Evt. ook fascie, spieren en bot betrokken ▪ Sclerodermie en coup de sabre - Op het voorhoofd, met aantasting schedelbot - Kan uitbreiden naar gelaat en mond <span>

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SCLERODERMA CIRCUMSCRIPTUM Kliniek

  • ▪ Scleroderma morphea (sclerodermie en plaques)
    • - Op romp (soms gezicht/extremiteiten)
    • - Begin met niet-jeukende rode plekken
    • - Later bruine verkleuring en verharding
  • ▪ Scleroderma linearis
    • - Aan extremiteiten (soms halfzijdig over lichaam)
    • - Langgerekte sclerotische gebieden, met veel hyper-/depigmentatie
    • - Evt. ook fascie, spieren en bot betrokken
  • ▪ Sclerodermie en coup de sabre
    • [...]
Answer
- Op het voorhoofd, met aantasting schedelbot- Kan uitbreiden naar gelaat en mond

statusnot learnedmeasured difficulty37% [default]last interval [days]               
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- Aan extremiteiten (soms halfzijdig over lichaam) - Langgerekte sclerotische gebieden, met veel hyper-/depigmentatie - Evt. ook fascie, spieren en bot betrokken ▪ Sclerodermie en coup de sabre <span>- Op het voorhoofd, met aantasting schedelbot - Kan uitbreiden naar gelaat en mond <span>

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SCLERODERMA CIRCUMSCRIPTUM

  • Behandeling 2

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GRANULOMA ANNULARE

  • Epidemiologie 3
  • Etiologie 1



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GRANULOMA ANNULARE

  • Kliniek 4

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GRANULOMA ANNULARE

  • Histologie 2
  • Behandeling 2



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DERMATOMYOSITIS

  • Epidemiologie 3
  • Etiologie/pathogenese 1



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DERMATOMYOSITIS

  • Kliniek 7



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DERMATOMYOSITIS

  • Behandeling 2



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ALOPECIA AREATA

  • Etiologie/pathogenese 2
  • Kliniek 4
  • Behandeling 3



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FOTODERMATOSEN

  • Etiologie/pathogenese 3
  • Kliniek 8
  • Diagnostiek 2
  • Behandeling 4



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TINEA MANUS

  • Etiologie/pathogenese 1
  • Kliniek 4
  • Diagnostiek 1
  • Behandeling 1
    • Systemische antimycotica, 12 weken lang



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VERRUCA SEBORRHOICA (BASALE CELPAPILLOOM)

  • Kliniek 2
  • Histopathologie 1
  • Behandeling 1



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CYSTEN EN PSEUDOCYSTEN

  • Cyste
  • Pseudocyste
  • Atheroom cyste / Trichilemmale cyste: op de behaarde hoofdhuid van volwassenen.
  • Miliumcyste



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KERATO-ACANTHOOM

  • Kliniek
  • Histologie
  • DD
  • Therapie



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ZWEETKLIERTUMOREN

  • Kliniek
  • Therapie



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TALGKLIERTUMOREN

  • Naevus sebaceus
  • Naevus sebaceus senilis
  • Fordyce-vlekjes



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CHONDRODERMATITIS NODULARIS HELICIS

  • Kliniek 1
  • Therapie 3



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TUMOREN UITGAANDE VAN MELANOCYTEN

  • Kliniek 5



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TUMOREN UITGAANDE VAN HET BINDWEEFSEL

  • 4



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LIPOOM

  • Kliniek
  • Therapie



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HEMANGIOMEN

  • Tubereuze, tuberocaverneuze en caverneuze hemangiomen
  • Pathogenese
  • Kliniek 3
  • Therapie 2



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Neavus flammeus/ wijnvlek

  • Kliniek 5
  • Therapie 1



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Neavus teleangiectatius/ooievaarspik

  • Kliniek
  • Therapie



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V ERWORVEN VASCULAIRE AFWIJKINGEN
Answer
  • Neavus araneus/ spider naevus
  • Angioma senile
  • Granuloma teleangiectaticum

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Neavus araneus/ spider naevus



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Angioma senile



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Granuloma teleangiectaticum:



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PREMALIGNE TUMOREN > ACTINISCHE KERATOSEN

  • Epidemiologie 2
  • Kliniek 3



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PREMALIGNE TUMOREN > ACTINISCHE KERATOSEN

  • Histopathologie 2
  • Behandeling 3



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MALIGNE TUMOREN CARCINOMA SPINOCELLULARE

Intra-epitheliaal carcinoom

  • Klinisch beeld 2
  • Histopathologie 3
  • DD 2
  • Behandeling 3



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MALIGNE TUMOREN CARCINOMA SPINOCELLULARE (PLAVEISELCELCARCINOOM)

  • Klinisch beeld 4
  • Behandeling 2



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CARCINOMA BASOCELLULARE

  • Etiologie / Pathogenese 2
  • Kliniek 2



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  • Nodulair basalioom: 0,5-2 cm grote huidkleurige tumor met fijne teleangiëctasieën
  • Ulcus rodens: ulcererend basalioom, kan zeer grote afmetingen aannemen
  • Cicatriserend basalioom: weinig geïnfiltreerd, groeit met vorming van keloïd, meestal witgele kleur
  • Superficieel basalioom: zeer oppervlakkig groeiend. Kan sterk lijken op psoriasis laesie, maar heeft een enigszins geïnfiltreerde rand met telangiëctasieën.
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Question
  • [...]: 0,5-2 cm grote huidkleurige tumor met fijne teleangiëctasieën
  • [...] : ulcererend basalioom, kan zeer grote afmetingen aannemen
  • [...] : weinig geïnfiltreerd, groeit met vorming van keloïd, meestal witgele kleur
  • [...] : zeer oppervlakkig groeiend. Kan sterk lijken op psoriasis laesie, maar heeft een enigszins geïnfiltreerde rand met telangiëctasieën.
Answer
Nodulair basalioom

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Nodulair basalioom: 0,5-2 cm grote huidkleurige tumor met fijne teleangiëctasieën ▪ Ulcus rodens: ulcererend basalioom, kan zeer grote afmetingen aannemen ▪ Cicatriserend basalioom: weinig geïnfiltreerd,

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Flashcard 5039650114828

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  • Nodulair basalioom: [...]
  • Ulcus rodens: ulcererend basalioom, kan zeer grote afmetingen aannemen
  • Cicatriserend basalioom: weinig geïnfiltreerd, groeit met vorming van keloïd, meestal witgele kleur
  • Superficieel basalioom: zeer oppervlakkig groeiend. Kan sterk lijken op psoriasis laesie, maar heeft een enigszins geïnfiltreerde rand met telangiëctasieën.
Answer
0,5-2 cm grote huidkleurige tumor met fijne teleangiëctasieën

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▪ Nodulair basalioom: 0,5-2 cm grote huidkleurige tumor met fijne teleangiëctasieën ▪ Ulcus rodens: ulcererend basalioom, kan zeer grote afmetingen aannemen ▪ Cicatriserend basalioom: weinig geïnfiltreerd, groeit met vorming van keloïd, meestal witgele kleur ▪ Superfic

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Flashcard 5039651687692

Question
  • Nodulair basalioom: 0,5-2 cm grote huidkleurige tumor met fijne teleangiëctasieën
  • Ulcus rodens: [...]
  • Cicatriserend basalioom: weinig geïnfiltreerd, groeit met vorming van keloïd, meestal witgele kleur
  • Superficieel basalioom: zeer oppervlakkig groeiend. Kan sterk lijken op psoriasis laesie, maar heeft een enigszins geïnfiltreerde rand met telangiëctasieën.
Answer
ulcererend basalioom, kan zeer grote afmetingen aannemen

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▪ Nodulair basalioom: 0,5-2 cm grote huidkleurige tumor met fijne teleangiëctasieën ▪ Ulcus rodens: ulcererend basalioom, kan zeer grote afmetingen aannemen ▪ Cicatriserend basalioom: weinig geïnfiltreerd, groeit met vorming van keloïd, meestal witgele kleur ▪ Superficieel basalioom: zeer oppervlakkig groeiend. Kan sterk lijken op psoriasis

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Flashcard 5039653260556

Question
  • Nodulair basalioom: 0,5-2 cm grote huidkleurige tumor met fijne teleangiëctasieën
  • Ulcus rodens: ulcererend basalioom, kan zeer grote afmetingen aannemen
  • Cicatriserend basalioom: [...]
  • Superficieel basalioom: zeer oppervlakkig groeiend. Kan sterk lijken op psoriasis laesie, maar heeft een enigszins geïnfiltreerde rand met telangiëctasieën.
Answer
weinig geïnfiltreerd, groeit met vorming van keloïd, meestal witgele kleur

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an> ▪ Nodulair basalioom: 0,5-2 cm grote huidkleurige tumor met fijne teleangiëctasieën ▪ Ulcus rodens: ulcererend basalioom, kan zeer grote afmetingen aannemen ▪ Cicatriserend basalioom: weinig geïnfiltreerd, groeit met vorming van keloïd, meestal witgele kleur ▪ Superficieel basalioom: zeer oppervlakkig groeiend. Kan sterk lijken op psoriasis laesie, maar heeft een enigszins geïnfiltreerde rand met telangiëctasieën. <span>

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Flashcard 5039654833420

Question
  • Nodulair basalioom: 0,5-2 cm grote huidkleurige tumor met fijne teleangiëctasieën
  • Ulcus rodens: ulcererend basalioom, kan zeer grote afmetingen aannemen
  • Cicatriserend basalioom: weinig geïnfiltreerd, groeit met vorming van keloïd, meestal witgele kleur
  • Superficieel basalioom: [...]
Answer
zeer oppervlakkig groeiend. Kan sterk lijken op psoriasis laesie, maar heeft een enigszins geïnfiltreerde rand met telangiëctasieën.

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rodens: ulcererend basalioom, kan zeer grote afmetingen aannemen ▪ Cicatriserend basalioom: weinig geïnfiltreerd, groeit met vorming van keloïd, meestal witgele kleur ▪ Superficieel basalioom: <span>zeer oppervlakkig groeiend. Kan sterk lijken op psoriasis laesie, maar heeft een enigszins geïnfiltreerde rand met telangiëctasieën. <span>

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CARCINOMA BASOCELLULARE

  • Histopathologie 2
  • Behandeling 5



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MELANOMEN

  • Kliniek 4



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MELANOMEN

  • Risicofactoren 6



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MELANOMEN

  • Histopathologie 5



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Prognose MELANOMEN

  • ▪ Stadium I: beperkt tot primaire lokalisatie; 80% 5-jaarsoverleving
  • ▪ Stadium II: regionale metastasen (lymfogeen); 25% 5-jaarsoverleving
  • ▪ Stadium III: metastasen op afstand; infauste prognose van enkele maanden

  • ▪ Breslow-dikte < 1 mm 5-jaarsoverleving ongeveer 100%
  • ▪ Breslow-dikte 1-2 mm 5-jaarsoverleving 90%
  • ▪ Breslow-dikte 2-4 mm 5-jaarsoverleving 70%
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Flashcard 5039673707788

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Prognose MELANOMEN

  • ▪ Stadium I: [...]
  • ▪ Stadium II: regionale metastasen (lymfogeen); 25% 5-jaarsoverleving
  • ▪ Stadium III: metastasen op afstand; infauste prognose van enkele maanden

  • ▪ Breslow-dikte < 1 mm 5-jaarsoverleving ongeveer 100%
  • ▪ Breslow-dikte 1-2 mm 5-jaarsoverleving 90%
  • ▪ Breslow-dikte 2-4 mm 5-jaarsoverleving 70%
Answer
beperkt tot primaire lokalisatie; 80% 5-jaarsoverleving

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Prognose MELANOMEN ▪ Stadium I: beperkt tot primaire lokalisatie; 80% 5-jaarsoverleving ▪ Stadium II: regionale metastasen (lymfogeen); 25% 5-jaarsoverleving ▪ Stadium III: metastasen op afstand; infauste prognose van enkele maanden ▪ Breslow-dikte < 1 mm 5-jaarsoverlev

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Flashcard 5039675280652

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Prognose MELANOMEN

  • ▪ Stadium I: beperkt tot primaire lokalisatie; 80% 5-jaarsoverleving
  • ▪ Stadium II: [...]
  • ▪ Stadium III: metastasen op afstand; infauste prognose van enkele maanden

  • ▪ Breslow-dikte < 1 mm 5-jaarsoverleving ongeveer 100%
  • ▪ Breslow-dikte 1-2 mm 5-jaarsoverleving 90%
  • ▪ Breslow-dikte 2-4 mm 5-jaarsoverleving 70%
Answer
regionale metastasen (lymfogeen); 25% 5-jaarsoverleving

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Prognose MELANOMEN ▪ Stadium I: beperkt tot primaire lokalisatie; 80% 5-jaarsoverleving ▪ Stadium II: regionale metastasen (lymfogeen); 25% 5-jaarsoverleving ▪ Stadium III: metastasen op afstand; infauste prognose van enkele maanden ▪ Breslow-dikte < 1 mm 5-jaarsoverleving ongeveer 100% ▪ Breslow-dikte 1-2 mm 5-jaarsoverleving 90% ▪ Bresl

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Flashcard 5039676853516

Question

Prognose MELANOMEN

  • ▪ Stadium I: beperkt tot primaire lokalisatie; 80% 5-jaarsoverleving
  • ▪ Stadium II: regionale metastasen (lymfogeen); 25% 5-jaarsoverleving
  • ▪ Stadium III: [...]

  • ▪ Breslow-dikte < 1 mm 5-jaarsoverleving ongeveer 100%
  • ▪ Breslow-dikte 1-2 mm 5-jaarsoverleving 90%
  • ▪ Breslow-dikte 2-4 mm 5-jaarsoverleving 70%
Answer
metastasen op afstand; infauste prognose van enkele maanden

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Prognose MELANOMEN ▪ Stadium I: beperkt tot primaire lokalisatie; 80% 5-jaarsoverleving ▪ Stadium II: regionale metastasen (lymfogeen); 25% 5-jaarsoverleving ▪ Stadium III: metastasen op afstand; infauste prognose van enkele maanden ▪ Breslow-dikte < 1 mm 5-jaarsoverleving ongeveer 100% ▪ Breslow-dikte 1-2 mm 5-jaarsoverleving 90% ▪ Breslow-dikte 2-4 mm 5-jaarsoverleving 70%

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Flashcard 5039678426380

Question

Prognose MELANOMEN

  • ▪ Stadium I: beperkt tot primaire lokalisatie; 80% 5-jaarsoverleving
  • ▪ Stadium II: regionale metastasen (lymfogeen); 25% 5-jaarsoverleving
  • ▪ Stadium III: metastasen op afstand; infauste prognose van enkele maanden

  • ▪ Breslow-dikte < [...]
  • ▪ Breslow-dikte 1-2 mm 5-jaarsoverleving 90%
  • ▪ Breslow-dikte 2-4 mm 5-jaarsoverleving 70%
Answer
1 mm 5-jaarsoverleving ongeveer 100%

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atie; 80% 5-jaarsoverleving ▪ Stadium II: regionale metastasen (lymfogeen); 25% 5-jaarsoverleving ▪ Stadium III: metastasen op afstand; infauste prognose van enkele maanden ▪ Breslow-dikte < <span>1 mm 5-jaarsoverleving ongeveer 100% ▪ Breslow-dikte 1-2 mm 5-jaarsoverleving 90% ▪ Breslow-dikte 2-4 mm 5-jaarsoverleving 70% <span>

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Flashcard 5039679999244

Question

Prognose MELANOMEN

  • ▪ Stadium I: beperkt tot primaire lokalisatie; 80% 5-jaarsoverleving
  • ▪ Stadium II: regionale metastasen (lymfogeen); 25% 5-jaarsoverleving
  • ▪ Stadium III: metastasen op afstand; infauste prognose van enkele maanden

  • ▪ Breslow-dikte < 1 mm 5-jaarsoverleving ongeveer 100%
  • ▪ Breslow-dikte [...]
  • ▪ Breslow-dikte 2-4 mm 5-jaarsoverleving 70%
Answer
1-2 mm 5-jaarsoverleving 90%

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etastasen (lymfogeen); 25% 5-jaarsoverleving ▪ Stadium III: metastasen op afstand; infauste prognose van enkele maanden ▪ Breslow-dikte < 1 mm 5-jaarsoverleving ongeveer 100% ▪ Breslow-dikte <span>1-2 mm 5-jaarsoverleving 90% ▪ Breslow-dikte 2-4 mm 5-jaarsoverleving 70% <span>

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Prognose MELANOMEN

  • ▪ Stadium I: beperkt tot primaire lokalisatie; 80% 5-jaarsoverleving
  • ▪ Stadium II: regionale metastasen (lymfogeen); 25% 5-jaarsoverleving
  • ▪ Stadium III: metastasen op afstand; infauste prognose van enkele maanden

  • ▪ Breslow-dikte < 1 mm 5-jaarsoverleving ongeveer 100%
  • ▪ Breslow-dikte 1-2 mm 5-jaarsoverleving 90%
  • ▪ Breslow-dikte [...]
Answer
2-4 mm 5-jaarsoverleving 70%

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▪ Stadium III: metastasen op afstand; infauste prognose van enkele maanden ▪ Breslow-dikte < 1 mm 5-jaarsoverleving ongeveer 100% ▪ Breslow-dikte 1-2 mm 5-jaarsoverleving 90% ▪ Breslow-dikte <span>2-4 mm 5-jaarsoverleving 70% <span>

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MELANOMEN

  • Behandeling 5



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Crème



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Zalf



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Pasta



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Koelpasta



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Lotion



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Schudmengsel



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Hydrogel



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CORTICOSTEROÏDEN

  • Eigenschappen 6



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CORTICOSTEROÏDEN

  • Classificatie 4



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stappenplan 8



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anamnese 6



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lichamelijk onderzoek 3



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anatomie huid
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anatomie huid



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dd erytheem 8



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papuleuze dermatozen 11



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dd purpera 2



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dd eczemen 4



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dd erythomatosquameuze dermatosen 4



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dd vesiculo-bulleuze dermatosen 6



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dd mondslijmvleesafwijken 3



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dd pusteleuze dermatosen 5



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dd noduleuze dermatosen 2



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dd ulcereuze dermatosen 2



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dd trichosen 4

dd keratosen 1




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dd

  • dyschromie 2
  • sclerose 1
  • onychose 2



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typen allergie 4



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plaats



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rangschikking

  • groepering 10
  • uitbreiding 5



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omvang 5



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vorm 21



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omtrek 4



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kleur 4



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Efflorescentie 23



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PROVOKE voorbeeld



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#alma #o-livro-dos-espíritos
Julgamos mais lógico tomá-lo na sua acepção vulgar e por isso chamamos ALMA ao ser imaterial e individual que em nós reside e sobrevive ao corpo. Mesmo quando esse ser não existisse, não passasse de produto da imaginação, ainda assim fora preciso um termo para designá-lo.
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#o-livro-dos-espiritos #princípio-vital
Princípio vital [é] o princípio da vida material e orgânica, qualquer que seja a fonte donde promane, princípio esse comum a todos os seres vivos, desde as plantas até o ho- mem. Pois que pode haver vida com exclusão da faculdade de pensar, o princípio vital é coisa distinta e independente.
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#fluido-vital #o-livro-dos-espíritos
Segundo outros, e esta é a idéia mais comum, ele [o princípio vital] reside em um fluido especial, universalmente espalhado e do qual cada ser absorve e assimila uma parcela durante a vida, tal como os corpos inertes absorvem a luz. Esse seria então o fluido vital que, na opinião de alguns, em nada difere do fluido elétrico animalizado, ao qual também se dão os nomes de fluido magnético, fluido nervoso, etc.
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#espécie-humana #inteligência #o-livro-dos-espíritos #pensamento #senso-moral
(...) entre as espécies orgânicas dotadas de inteligência e de pensamento há uma dotada também de um senso moral especial, que lhe dá incontestável superioridade sobre as outras: a espécie humana.
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Question

Syphilis

  • Manifestations ophtalmiques
    • À interpréter comme [...]

Answer

une neurosyphilis « précoce »


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érieure, papil- lite, névrite optique), d'où l'importance d'un bon interrogatoire à la recherche d'anomalies de la vision (baisse acuité visuelle, phosphènes, douleurs…) : – à interpréter comme <span>une neurosyphilis « précoce », – justifiant la pratique d'une ponction lombaire et, quel que soit le résultat de cette der- nière, un traitement par pénicilline G pendant 14 jours ; • atteinte d'une paire crânienne

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Question

Syphilis

  • Manifestations ophtalmiques
    • Justifiant la pratique d'une [...]

Answer

ponction lombaire


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bon interrogatoire à la recherche d'anomalies de la vision (baisse acuité visuelle, phosphènes, douleurs…) : – à interpréter comme une neurosyphilis « précoce », – justifiant la pratique d'une <span>ponction lombaire et, quel que soit le résultat de cette der- nière, un traitement par pénicilline G pendant 14 jours ; • atteinte d'une paire crânienne : hypoacousie ou acouphènes, paralysie faciale… qu

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Quelles sont les 4 principales manifestations ophtalmiques de la syphilis ?
Answer

Surtout uvéite antérieure

Mais aussi :

  • Uvéite postérieure

  • Papillite

  • Névrite optique


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• manifestations ophtalmiques (surtout uvéite antérieure mais aussi uvéite postérieure, papil- lite, névrite optique), d'où l'importance d'un bon interrogatoire à la recherche d'anomalies de la vision (baisse acuité visuelle, phosphènes, douleurs…) : – à interpréter comme une neurosyphilis « précoce »

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Question

Syphilis

Le TPHA se positive entre le [...] et [...] jour du chancre

Answer

Entre le 7ème et 10ème jour du chancre


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Cinétique Le TPHA se positive entre le 7 e et 10 e jour du chancre. L'intensité de la réaction est cotée en dilution de 1/80 puis de 1/160, 1/320… Le titre du TPHA quantitatif n'est pas un bon marqueur de l'évolutivité de la mal

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Syphilis

Le titre du TPHA quantitatif est-il un bon marqueur de suivi de l'infection ?

Answer

NON

Le titre du TPHA quantitatif n'est pas un bon marqueur de l'évolutivité de la maladie ni de la réponse au traitement, car il varie de façon importante d'un examen à l'autre pour un même patient


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Cinétique Le TPHA se positive entre le 7 e et 10 e jour du chancre. L'intensité de la réaction est cotée en dilution de 1/80 puis de 1/160, 1/320… Le titre du TPHA quantitatif n'est pas un bon marqueur de l'évolutivité de la maladie ni de la réponse au traitement, car il varie de façon importante d'un examen à l'autre pour un même patient. Seul le TPHA qualitatif (« 0 » à « +++ ») est donc intéressant par sa positivité ou sa négativité

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Question

Syphilis

  • VDRL ( Venereal Disease Research Laboratory )
    • Il met en évidence, dans le sérum du patient, des anticorps [...].

Answer

anti-cardiolipidiques


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VDRL ( Venereal Disease Research Laboratory ) Il met en évidence, dans le sérum du patient, des anticorps anti-cardiolipidiques. Le VDRL n'est pas une réaction spécifique des tréponématoses (+++). Une sérologie syphilitique faussement positive (VDRL positif, TPHA négatif) s'observe au cours de maladies dysimmuni

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Question

Syphilis

Une sérologie syphilitique faussement positive (VDRL positif, TPHA négatif) peut s'observer au cours de certaines maladies infectieuses à [...] ou dans les [...]

Answer

Mycoplasma pneumoniae ou dans les borrélioses


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tif, TPHA négatif) s'observe au cours de maladies dysimmunitaires, notamment au cours du lupus et du syndrome des anticorps anti-phospholipides, ainsi que dans certaines maladies infectieuses à <span>Mycoplasma pneumo- niae ou dans les borrélioses <span>

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Question

Les partenaires sexuels sont systématiquement dépistés, puis traités :

  • Syphilis :
    • Traitement d’emblée si le dernier rapport sexuel date de moins de [...] semaines
    • Traitement selon les résultats de la sérologie s’il date de plus de [...] semaines

Answer

6 semaines


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dépistés, puis traités : Infection à gonocoque et Chlamydia : traitement d’emblée du/des partenaire(s) régulier(s). Syphilis : Traitement d’emblée si le dernier rapport sexuel date de moins de <span>6 semaines Traitement selon les résultats de la sérologie s’il date de plus de 6 semaines. Infection à HPV : pas de dépistage en dehors du frottis cervical et/ou de l'examen prodologique







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Question

Syphilis

On considère que le traitement est efficace quand le titre du VDRL est divisé par [...] (deux dilutions), 6 mois après le traitement

Answer

VDRL divisé par 4 après 6 mois


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La surveillance biologique de l'efficacité du traitement se fait sur le VDRL quantitatif (+++). On considère que le traitement est efficace quand le titre du VDRL est divisé par 4 (deux dilutions), 6 mois après le traitement

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Question

Syphilis

Le VDRL doit être négatif [...] après le traitement d'une syphilis primaire et dans un délai de [...] après traitement d'une syphilis secondaire

Answer

1 an pour syphilis primaire

2 ans pour syphilis secondaire


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Le VDRL doit être négatif 1 an après le traitement d'une syphilis primaire et dans un délai de 2 ans après traitement d'une syphilis secondaire

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Question

Syphilis

  • Evolution récente de la stratégie diagnostique :
    • Il est désormais recommandé que le dépistage initial soit fait par un test [...] automatisé qualitatif, confirmé en cas de positivité par un test [...] (VDRL ou RPR) quantitatif.

Answer

Dépistage initial par test tréponémique automatisé (EIA, ELISA) qualitatif

Confirmé en cas de positivité par un test non tréponémique (VDRL ou RPR) quantitatif


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Evolution récente de la stratégie diagnostique : il est désormais recommandé que le dépistage initial soit fait par un test tréponémique automatisé (EIA, ELISA) qualitatif, confirmé en cas de positivité par un test non tréponémique (VDRL ou RPR) quantitatif. Positivité en général 10 jours après le chancre (test tréponémi







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#345 #Cours #Dermatologie #Erysipele #Facultaires #Grosse #Jambe #Rouge #has-images
[unknown IMAGE 5042878156044]
Question
Marqueurs de sévérité de la dermo-hypodermite ?
[unknown IMAGE 5037254905100]

statusnot learnedmeasured difficulty37% [default]last interval [days]               
repetition number in this series0memorised on               scheduled repetition               
scheduled repetition interval               last repetition or drill

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Flashcard 5042882612492

Tags
#345 #Cours #Dermatologie #Erysipele #Facultaires #Grosse #Jambe #Rouge #has-images
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statusnot learnedmeasured difficulty37% [default]last interval [days]               
repetition number in this series0memorised on               scheduled repetition               
scheduled repetition interval               last repetition or drill

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Flashcard 5042886020364

Tags
#345 #Cours #Dermatologie #Erysipele #Facultaires #Grosse #Jambe #Rouge
Question

Erysipèle

Forme habituelle
• Plaque érythémateuse, œdémateuse, circonscrite et douloureuse à la palpation (bourrelet périphérique marqué observé uniquement au niveau [...])

Answer

Bourrelet au niveau du VISAGE


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Parent (intermediate) annotation

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rition du placard cutané inflammatoire. • Plaque érythémateuse, œdémateuse, circonscrite et douloureuse à la palpation (figure 345.1) (bourrelet périphérique marqué observé uniquement au niveau <span>du visage). • Parfois décollements bulleux superficiels, conséquence mécanique de l'œdème dermique, ou purpura sur le placard (figure 345.2). • Adénopathies inflammatoires homolatérales fréquemme

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Flashcard 5042887593228

Tags
#345 #Cours #Dermatologie #Erysipele #Facultaires #Grosse #Jambe #Rouge
Question

Erysipèle

Forme habituelle

• Amélioration des signes locaux plus lente, en [...].

Answer

1 semaine


statusnot learnedmeasured difficulty37% [default]last interval [days]               
repeti