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In biology, epigenetics is the study of heritable phenotype changes that do not involve alterations in the DNA sequence.[1]
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Epigenetics - Wikipedia
heritable DNA and histone modifications that affect the expression of a gene without a change in its nucleotide sequence. For other uses, see Epigenetic (disambiguation). Epigenetic mechanisms <span>In biology, epigenetics is the study of heritable phenotype changes that do not involve alterations in the DNA sequence.[1] The Greek prefix epi- (ἐπι- "over, outside of, around") in epigenetics implies features that are "on top of" or "in addition to" the traditional genetic basis for inheritance.[2] Epigen



Annotation 6705433152780

epigenetics implies features that are "on top of" or "in addition to" the traditional genetic basis for inheritance.[2]
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Epigenetics - Wikipedia
mechanisms In biology, epigenetics is the study of heritable phenotype changes that do not involve alterations in the DNA sequence.[1] The Greek prefix epi- (ἐπι- "over, outside of, around") in <span>epigenetics implies features that are "on top of" or "in addition to" the traditional genetic basis for inheritance.[2] Epigenetics most often involves changes that affect gene activity and expression, but the term can also be used to describe any heritable phenotypic change. Such effects on cellular and



Annotation 6705434725644

Epigenetics most often involves changes that affect gene activity and expression, but the term can also be used to describe any heritable phenotypic change.
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Epigenetics - Wikipedia
A sequence.[1] The Greek prefix epi- (ἐπι- "over, outside of, around") in epigenetics implies features that are "on top of" or "in addition to" the traditional genetic basis for inheritance.[2] <span>Epigenetics most often involves changes that affect gene activity and expression, but the term can also be used to describe any heritable phenotypic change. Such effects on cellular and physiological phenotypic traits may result from external or environmental factors, or be part of normal development. The term also refers to the changes the



Annotation 6705436298508

Such effects on cellular and physiological phenotypic traits may result from external or environmental factors, or be part of normal development.
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Epigenetics - Wikipedia
al genetic basis for inheritance.[2] Epigenetics most often involves changes that affect gene activity and expression, but the term can also be used to describe any heritable phenotypic change. <span>Such effects on cellular and physiological phenotypic traits may result from external or environmental factors, or be part of normal development. The term also refers to the changes themselves: functionally relevant changes to the genome that do not involve a change in the nucleotide sequence. Examples of mechanisms that produce



Annotation 6705437871372

MicroRNAs (miRNAs) are members of non-coding RNAs that range in size from 17 to 25 nucleotides. miRNAs regulate a large variety of biological functions in plants and animals.[72] So far, in 2013, about 2000 miRNAs have been discovered in humans and these can be found online in a miRNA database.[73] Each miRNA expressed in a cell may target about 100 to 200 messenger RNAs(mRNAs) that it downregulates.[74] Most of the downregulation of mRNAs occurs by causing the decay of the targeted mRNA, while some downregulation occurs at the level of translation into protein.[75]
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Epigenetics - Wikipedia
y of sperm RNA is transmitted from the father, but there is recent evidence that this epigenetic information can lead to visible changes in several generations of offspring.[71] MicroRNAs[edit] <span>MicroRNAs (miRNAs) are members of non-coding RNAs that range in size from 17 to 25 nucleotides. miRNAs regulate a large variety of biological functions in plants and animals.[72] So far, in 2013, about 2000 miRNAs have been discovered in humans and these can be found online in a miRNA database.[73] Each miRNA expressed in a cell may target about 100 to 200 messenger RNAs(mRNAs) that it downregulates.[74] Most of the downregulation of mRNAs occurs by causing the decay of the targeted mRNA, while some downregulation occurs at the level of translation into protein.[75] It appears that about 60% of human protein coding genes are regulated by miRNAs.[76] Many miRNAs are epigenetically regulated. About 50% of miRNA genes are associated with CpG islands,[